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Latest Estrogen Stories

2013-04-02 12:34:46

A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive breast cancer cells that are resistant to hormone therapies such as tamoxifen, aromatase inhibitors or fulvestrant. Resistance to hormone therapy is reported in almost half of ER-positive breast cancer patients and no cure is currently available. The fact that...

2013-04-01 10:36:59

LA Biomed researcher studied the effects of combined hormone therapy Dr. Rowan Chlebowski, MD, PhD, Los Angeles Biomedical Research Institute lead researcher and author of a study released March 29 by the Journal of the National Cancer Institute, issued the following statement regarding the latest findings from the Women's Health Initiative, the largest-ever study of hormonal therapy in post-menopausal women. The study Dr. Chlebowski authored reported that estrogen plus progestin use is...

2013-04-01 10:31:57

Estrogen plus progestin use is linked with increased breast cancer incidence. In addition, prognosis is similar for both users and nonusers of combined hormone therapy, suggesting that mortality from breast cancer may be higher for hormone therapy users as well, according to a study published March 29 in the Journal of the National Cancer Institute. In the Women's Health Initiative (WHI) randomized trial, estrogen plus progestin was associated with an increase in both breast cancer...

Sequencing Cancer's DNA May Yield Better Prevention Strategies
2013-03-28 06:16:38

redOrbit Staff & Wire Reports - Your Universe Online Researchers at the Mayo Clinic Cancer Center have identified new DNA sequences associated with breast and ovarian cancers that help reveal the underlying causes of these diseases so new prevention strategies can be devised. The findings appear in three studies in the journals PLoS Genetics and Nature Genetics. In the first study, published in the journal PLoS Genetics, researchers looked at variations across the genomes of...

Discovery Of New Genes May Help Assess Risk And Prevent Breast Cancer
2013-03-20 10:17:03

April Flowers for redOrbit.com - Your Universe Online A new study from Northwestern Medicine has identified a set of genes that may predict which women are at high risk for getting breast cancer that is sensitive to estrogen. These women would be helped by taking drugs to prevent the cancer's development. The results of the study will be published in the journal Cancer Prevention Research. "We now have the possibility of predicting if a preventive drug will work for a woman at high...

2013-03-18 20:44:01

Oral estrogen therapy for menopausal women is associated with an increased risk of gallbladder surgery, according to a large-scale study of more than 70 000 women in France published in CMAJ (Canadian Medical Association Journal). Women who took estrogen therapy through skin patches or gels did not appear to be at increased risk. Gallstone disease is common in developed countries, and women over age 50 are most at risk. Other risk factors include obesity, diabetes, high cholesterol,...

FDA Rejects Two Menopause Drugs Deemed Ineffective
2013-03-06 10:25:50

redOrbit Staff & Wire Reports - Your Universe Online A Food and Drug Administration (FDA) advisory committee rejected on Monday two proposed menopause drugs designed to reduce the frequency and severity of hot flashes. In a 12-to-2 vote, the advisory committee for reproductive health drugs voted against approving Depomed´s extended-release gabapentin, known as Sefelsa, which contains a form of an active ingredient used in some anti-seizure medicines. It also rejected in a vote...

2013-02-08 14:23:59

Long-acting reversible contraception with progestin appears safe but merits further study Highlights of this news release: -Six-month study finds that progestin-releasing contraceptives show a slight negative impact on metabolic markers, raising the risk for type 2 diabetes. -Contraceptive implants under the skin increase the risk more than uterine implants. -Longer and larger studies are needed to see if metabolic changes are temporary or long-term. A first-of-its-kind study by...


Word of the Day
out-herod
  • In the phrase to out-herod Herod, to be more violent than Herod (as represented in the old mystery plays); hence, to exceed in any excess of evil.
Herod refers to 'Herod the Great,' a Roman client king and 'a madman who murdered his own family and a great many rabbis.' According to the OED, the term is 'chiefly with allusion to Shakespeare's use' in Hamlet.
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