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Latest European Molecular Biology Laboratory Stories

2011-08-31 14:36:03

Minimum information about a bioactive entity An international consortium of pharmaceutical companies, public and commercial data providers and academic groups has agreed on a new standard for describing the effect of a compound on a biological entity. Published in Nature Reviews Drug Discovery, the Minimum Information about a Bioactive Entity (MIABE) standard makes it possible to enhance the interchange of public data on drug discovery success and attrition. Every day, pharma, biotech...

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2011-08-18 13:48:11

When an egg cell is being formed, the cellular machinery which separates chromosomes is extremely imprecise at fishing them out of the cell's interior, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have discovered. The unexpected degree of trial-and-error involved in this process could explain why errors in the number of chromosomes in the egg cell are the leading cause of miscarriages and severe congenital diseases such as trisomies like Down's...

2011-07-22 01:38:05

Specialist cells prune connections between neurons Gardeners know that some trees require regular pruning: some of their branches have to be cut so that others can grow stronger. The same is true of the developing brain: cells called microglia prune the connections between neurons, shaping how the brain is wired, scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, discovered. Published online today in Science, the findings could one day help understand...

2011-07-18 14:24:58

"ËœCord-stopper' protein complex makes chromosomes easier to move As any rock-climber knows, trailing a long length of rope behind you is not easy. A dangling length of rope is unwieldy and hard to manoeuvre, and can get tangled up or stuck on an outcropping. Cells face the same problem when dragging chromosomes apart during cell division. The chromosomes are pulled by their middle "“ the centromere "“ their arms trailing along behind. Just like climbers carry their rope...

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2011-04-21 07:40:00

The human digestive system, a hotbed of living bacteria, comes in three variations just as distinct as variations in blood type, according to a study released on Wednesday. These "enterotypes" are found in people around the world and exist independent of race, origin, diet, body mass index (BMI), age and state of health, the study says. Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, collaborators in the international MetaHIT consortium, and...

2011-04-13 03:00:00

AMSTERDAM, April 13, 2011 /PRNewswire-FirstCall/ -- - Reflect-Network Application Visualizes Interactions Between Molecular Biological Entities Elsevier, a world leading publisher of scientific, technical and medical information products and services, today announced the availability of a new application, Reflect-Network, on SciVerse Applications beta. The application was developed in partnership with the European Molecular Biology Laboratory (EMBL), Germany, and the Novo...

2011-03-24 17:45:54

Using synthetic biology to precisely label proteins Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have developed a new method which enables researchers to label any protein of their choice with any of a wide variety of previously available compounds, in living cells, by introducing a single reactive artificial amino acid. Published today in Angewandte Chemie, the new technique enables researchers to label even rare proteins very precisely for optical...

2011-03-21 17:01:00

New method for studying gene regulation Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have developed a new method for studying gene regulation, by employing a jumping gene as an informant. Published online today in Nature Genetics, the new method is called GROMIT. It enables researchers to systematically explore the very large part of our genome that does not code for proteins, and which likely plays a large role in making each of us unique, by...

2011-03-07 15:28:27

New method reveals genes' combined effects Scientists at the European Molecular Biology Laboratory (EMBL) and the German Cancer Research Centre (DKFZ), both in Heidelberg, Germany, have developed a new method that uncovers the combined effects of genes. Published online today in Nature Methods, it helps understand how different genes can amplify, cancel out or mask each others' effects, and enables scientists to suggest genes that interfere with each other in much the same manner that...

2011-02-04 12:31:10

Research could lead to new therapies In our not-so-distant evolutionary past, stress often meant imminent danger, and the risk of blood loss, so part of our body's stress response is to stock-pile blood-clotting factors. Scientists in the Molecular Medicine Partnership Unit (MMPU), a collaboration between the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the University of Heidelberg Medical Centre, have discovered how stressed cells boost the production of the key...


Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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