Latest Exocytosis Stories
In research published in this week’s online edition of Science (DOI: 10.1126/science.1244811), postdoc Nicholas Vyleta and Professor Peter Jonas of the Institute of Science and Technology Austria (IST Austria) uncover the existence of loose coupling between calcium channels and release sensors of exocytosis at a mature central synapse in the rodent brain.
Cells ingest proteins and engulf bacteria by a gymnastic, shape-shifting process called endocytosis.
The many factors that contribute to how cells communicate and function at the most basic level are still not fully understood, but researchers at Baylor College of Medicine have uncovered a mechanism that helps explain how intracellular membranes fuse, and in the process, created a new physiological membrane fusion model.
Just as we must take out the trash to keep our homes clean and safe, it is essential that our cells have mechanisms for dealing with wastes and worn-out proteins.
Neurons communicate via chemical transmitters which they store in the bubble-like synaptic vesicles and release as required.
The transmission of information from one neuron to the next is an unseen intricate ballet.
As part of the intricate ballet of synaptic transmission from one neuron to the next, tiny vesicles â€“ bubbles containing the chemical neurotransmitters that make information exchange possibleâ€”travel to the tip of neurons (synapses), where they fuse with the cell's membrane (a process called exocytosis).
Recycling is a critical component in the process of transmitting information from one neuron to the next, and a large protein called Tweek plays a critical role, said an international consortium of researchers led by Baylor College of Medicine (www.bcm.edu) in a report in the current issue of the journal Neuron.
In the bustling economy of the cell, little bubbles called vesicles serve as container ships, ferrying cargo to and from the port - the cell membrane.
Botox, used by Hollywood stars to smooth out facial wrinkles, is playing an important role in UQ research to understand how nerve cells communicate with each other.
- Stoppage; cessation (of labor).
- A standing still or idling (of mills, factories, etc.).