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Last updated on April 17, 2014 at 12:21 EDT

Latest Exon Stories

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2005-08-22 14:15:00

PITTSBURGH -- Important messages require accurate transmission. Big genes are especially challenging because they combine many coding segments (exons) that lie between long stretches of non-coding elements (introns). During processing, introns are snipped out and exons pasted together to form a template for proteins called messenger RNA (mRNA). Mistakes in RNA processing can reduce the expression of a functional protein or, worse, produce an abnormal protein that interferes with normal cell...

2005-07-12 02:05:00

A modification to an "ace" gene prediction program now enables scientists to predict the very beginnings of gene transcription start sites and where the first splice occurs thereby defining the first exon of the gene. The modification to the gene prediction software TWINSCAN is called N-SCAN. Michael Brent, Ph.D. professor of computer science at Washington University in St. Louis, together with Samuel S. Gross, then an undergraduate at Washington University, and Randall H. Brown, Ph.D., a...