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Latest Fibrous connective tissue Stories

Composite Nanofibers Developed, Next Chapter In Orthopaedic Biomaterials
2012-08-07 15:34:19

Bioengineered replacements for tendons, ligaments, the meniscus of the knee, and other tissues require re-creation of the exquisite architecture of these tissues in three dimensions. These fibrous, collagen-based tissues located throughout the body have an ordered structure that gives them their robust ability to bear extreme mechanical loading. Many labs have been designing treatments for ACL and meniscus tears of the knee, rotator cuff injuries, and Achilles tendon ruptures for patients...

2012-01-02 23:07:44

Researchers describe how increased production of a microRNA promotes progressive muscle deterioration in a mouse model of Duchenne muscular dystrophy (DMD), according to a study published online on January 2 in the Journal of Cell Biology (www.jcb.org). As DMD patients age, their damaged muscle cells are gradually replaced by collagen-rich, fibrous tissue. This muscle fibrosis is partly induced by the growth factor TGF-beta, which is highly activated in DMD patients, though exactly how...

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2009-06-16 15:20:00

Now researchers at the University of Washington are using the same principle for biomedical applications. Mixing chitosan, found in the shells of crabs and shrimp, with an industrial polyester creates a promising new material for the tiny tubes that support repair of a severed nerve, and could serve other medical uses. The hybrid fiber combines the biologically favorable qualities of the natural material with the mechanical strength of the synthetic polymer."A nerve guide requires very strict...

2009-01-30 11:46:17

Mice whose fat cells were allowed to grow larger than fat cells in normal mice developed healthy obesity, when fed a high-fat diet, U.S. researchers said. Researchers at the University of Texas Southwestern Medical Center in Dallas said the fat but healthy mice lacked a protein called collagen VI, which normally surrounds fat cells and limits how large they can grow -- like a cage around a water balloon. The mice lacking collagen VI fared much better metabolically than their counterparts...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'