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Latest Filopodia Stories

2013-11-25 13:17:05

In research published today in Nature Cell Biology, scientists from the EMBL Australia research team based at Monash University’s Australian Regenerative Medicine Institute (ARMI) have revealed new insights into how cells organize and form an early mammalian embryo. In an early mammalian embryo, just 8-cells large, the roundish cells do something they had never done before – something that would determine whether the embryo survived or failed. They change their shape. The cells become...

2013-03-14 16:56:01

First-in-class chemical compound might control metastases It´s the spread of the original cancer tumor that kills most people. That´s why cancer researchers vigorously search for drugs that can prevent metastases, the spread of cancer. The research team co-led by Angela Wandinger-Ness, PhD, and Larry Sklar, PhD, at the University of New Mexico Cancer Center has found a chemical compound that appears to control cell migration and adhesion, two important characteristics of...

2012-04-09 09:35:14

Cells on the move reach forward with lamellipodia and filopodia, cytoplasmic sheets and rods supported by branched networks or tight bundles of actin filaments. Cells without functional lamellipodia are still highly motile but lose their ability to stay on track, report researchers at the Stowers Institute for Medical Research in the April 9, 2012, online issue of the Journal of Cell Biology. Their study provides new insight into cell motility, a complex and integrated process, which, when...

2010-09-21 21:58:20

Insight may lead to better understanding of how cells respond to stress Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have discovered that a protein, zyxin, is necessary for the maintenance and repair of the cell's cytoskeleton, or internal framework, which serves as the muscle and bone of the cell. The research has implications for cancer, as well as other diseases, since alterations in the cytoskeleton are often associated with disease. The research was published...

2009-09-06 07:58:12

Researchers at the University of North Carolina at Chapel Hill School of Medicine have now discovered that establishing the neural wiring necessary to function normally depends on the ability of neurons to make finger-like projections of their membrane called filopodia.  In laying down the neural circuitry of the developing brain, billions of neurons must first migrate to their correct destinations and then form complex synaptic connections with their new neighbors. When the process goes...

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2008-11-25 11:40:00

Flip open any biology textbook and you're bound to see a complicated diagram of the inner workings of a cell, with its internal scaffolding, the  cytoskeleton, and how it maintains a cell's shape. Yet the fundamental question remains, which came first: the shape, or the skeleton?Now a research team led by Phong Tran, PhD, Assistant Professor of Cell and Developmental Biology at the University of Pennsylvania School of Medicine, has the answer: Both.The findings, published online this...


Word of the Day
abrosia
  • Wasting away as a result of abstinence from food.
The word 'abrosia' comes from a Greek roots meaning 'not' and 'eating'.