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Latest Flavivirus Stories

2010-11-17 22:04:00

Viruses have led scientists at Washington University School of Medicine in St. Louis to the discovery of a security system in host cells. Viruses that cause disease in animals beat the security system millennia ago. But now that researchers are aware of it, they can explore the possibility of bringing the system back into play in the fight against diseases such as sudden acute respiratory syndrome (SARS), West Nile virus, dengue and yellow fever. The findings, published in Nature, solve a...

2010-11-03 00:46:12

Researchers have learned the structure that results when an antibody binds to the West Nile virus, neutralizing the virus by locking up its infection mechanism. The information could help scientists develop a vaccine against the mosquito-borne disease. The findings show precisely how a key part of the antibody, called the antigen binding fragment, or Fab, attaches to two adjacent protein molecules that make up the virus's outer shell. This "crosslinking" attachment between molecules is...

2010-02-11 16:21:42

Finding has major implications for efforts to develop a first-ever vaccine against the dangerous infectious disorder A leading immunology research institute has validated the long-held and controversial hypothesis that antibodies "“ usually the "good guys" in the body's fight against viruses "“ instead contribute to severe dengue virus-induced disease, the La Jolla Institute for Allergy & Immunology announced today. The finding has major implications for the development of a...

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2009-12-14 09:45:00

University of Alberta researchers make math and science real for high-school students At least a dozen Alberta high-school calculus classrooms were exposed to the West Nile virus recently. Luckily, however, it wasn't literally the illness. University of Alberta education professor Stephen Norris and mathematics professor Gerda de Vries used the virus as a theoretical tool when they designed materials for use in an advanced high-school math course. The materials allow students to use...

2009-12-07 19:26:31

A new study shows that people who have been infected with West Nile virus may have persistent virus in their kidneys for years after initial infection, potentially leading to kidney problems. The research, which appears in the January 1 issue of The Journal of Infectious Diseases, is now available online (http://www.journals.uchicago.edu/doi/abs/10.1086/648731). Spread by infected mosquitoes, West Nile virus was first detected in the United States in 1999. Since then, approximately 25,000...

2009-11-06 07:35:00

SPRING VALLEY, Calif., Nov. 6 /PRNewswire/ -- Calbiotech, Inc. announced today that it has been awarded a Small Business Innovative Research (SBIR) Phase I contract by the U.S. Army Medical Research and Material command. Under terms of the agreement, Calbiotech will develop analyte specific reagents (ASRs) for the diagnosis of Dengue virus. Dengue virus is a mosquito-born flavivirus that represents a major threat to military forces deployed to tropical areas of the world. Due to its...

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2008-12-11 11:07:30

Research conducted at The University of Queensland could contribute to the development of a vaccine and cure for West Nile virus and Dengue fever. Led by Associate Professor Alexander Khromykh, a team of researchers from UQ's School of Molecular and Microbial Sciences identified a novel characteristic of the virus family to which these diseases belong. The team found all flaviviruses produced a small molecule which, among other functions, controlled the host's response to viral infection....

2008-11-06 06:00:21

SAN DIEGO, Nov. 6 /PRNewswire-FirstCall/ -- Vical Incorporated today announced that the Naval Medical Research Center (NMRC) plans to conduct preclinical and Phase 1 evaluation of a dengue DNA vaccine formulated with the company's Vaxfectin(R) adjuvant and delivered with the Biojector(R) 2000 needle-free injection system (Bioject Medical Technologies Inc.) (BULLETIN BOARD: BJCT) . In support of the program, Vical will manufacture the vaccine and the adjuvant under a $1.3 million contract,...

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2008-08-07 08:20:00

Researchers have discovered 305 genes for possible treatment of West Nile Virus. The genes were found by tracing all of the enzymes and proteins used by the West Nile virus to contaminate cells. "It comprises a dictionary of all of these genes that are critical for West Nile virus infection of a cell," said Dr. Erol Fikrig of Yale University. Fikrig's study was published in the journal Nature on Wednesday. According to the U.S. Centers for Disease Control and Prevention, West Nile virus...

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2008-05-15 11:25:20

Solving the mystery of disease originsBefore West Nile virus arrived in this country, we had (and still have) a home-grown relative of this pathogen. An epidemic of unknown origin exploded around St. Louis, Missouri in the autumn of 1933, a disease that is now known to be transmitted by mosquitoes from birds to people. Now, a new analysis of the genome of St. Louis encephalitis completed at the Sackler Institute for Comparative Genomics at the American Museum of Natural History (AMNH) is...


Latest Flavivirus Reference Libraries

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2011-01-12 16:33:15

Dengue fever and dengue hemorrhagic fever (DHF), caused by the dengue virus, is among the spectrum of acute febrile tropical disease and is transmitted by mosquitoes. Occurring mainly in the tropics it can be life threatening and is caused by four closely related virus stereotypes of the genus Flavivirus. It was identified and named in 1779. It has a nickname of "breakbone fever" due to it causing sever generalized bodyache. It tends to be more prevalent in the urban districts of its range...

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2011-01-11 13:44:52

Flavivirus is a genus of the family Flaviviridae. This genus includes the West Nile Virus, Dengue Virus, Tick-borne Encephalitis virus, yellow fever virus, and quite a few others. Flaviviruses get their name from the yellow fever virus. Flavus means yellow in Latin. Yellow fever was named because if caused yellow jaundice in victims. Mosquitoes and ticks transmit these viruses by biting people. Human infections are usually incidental since humans are unable to replicate the virus. Yellow...

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Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
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