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Latest Flavivirus Stories

2010-02-11 16:21:42

Finding has major implications for efforts to develop a first-ever vaccine against the dangerous infectious disorder A leading immunology research institute has validated the long-held and controversial hypothesis that antibodies "“ usually the "good guys" in the body's fight against viruses "“ instead contribute to severe dengue virus-induced disease, the La Jolla Institute for Allergy & Immunology announced today. The finding has major implications for the development of a...

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2009-12-14 09:45:00

University of Alberta researchers make math and science real for high-school students At least a dozen Alberta high-school calculus classrooms were exposed to the West Nile virus recently. Luckily, however, it wasn't literally the illness. University of Alberta education professor Stephen Norris and mathematics professor Gerda de Vries used the virus as a theoretical tool when they designed materials for use in an advanced high-school math course. The materials allow students to use...

2009-12-07 19:26:31

A new study shows that people who have been infected with West Nile virus may have persistent virus in their kidneys for years after initial infection, potentially leading to kidney problems. The research, which appears in the January 1 issue of The Journal of Infectious Diseases, is now available online (http://www.journals.uchicago.edu/doi/abs/10.1086/648731). Spread by infected mosquitoes, West Nile virus was first detected in the United States in 1999. Since then, approximately 25,000...

2009-11-06 07:35:00

SPRING VALLEY, Calif., Nov. 6 /PRNewswire/ -- Calbiotech, Inc. announced today that it has been awarded a Small Business Innovative Research (SBIR) Phase I contract by the U.S. Army Medical Research and Material command. Under terms of the agreement, Calbiotech will develop analyte specific reagents (ASRs) for the diagnosis of Dengue virus. Dengue virus is a mosquito-born flavivirus that represents a major threat to military forces deployed to tropical areas of the world. Due to its...

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2008-12-11 11:07:30

Research conducted at The University of Queensland could contribute to the development of a vaccine and cure for West Nile virus and Dengue fever. Led by Associate Professor Alexander Khromykh, a team of researchers from UQ's School of Molecular and Microbial Sciences identified a novel characteristic of the virus family to which these diseases belong. The team found all flaviviruses produced a small molecule which, among other functions, controlled the host's response to viral infection....

2008-11-06 06:00:21

SAN DIEGO, Nov. 6 /PRNewswire-FirstCall/ -- Vical Incorporated today announced that the Naval Medical Research Center (NMRC) plans to conduct preclinical and Phase 1 evaluation of a dengue DNA vaccine formulated with the company's Vaxfectin(R) adjuvant and delivered with the Biojector(R) 2000 needle-free injection system (Bioject Medical Technologies Inc.) (BULLETIN BOARD: BJCT) . In support of the program, Vical will manufacture the vaccine and the adjuvant under a $1.3 million contract,...

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2008-08-07 08:20:00

Researchers have discovered 305 genes for possible treatment of West Nile Virus. The genes were found by tracing all of the enzymes and proteins used by the West Nile virus to contaminate cells. "It comprises a dictionary of all of these genes that are critical for West Nile virus infection of a cell," said Dr. Erol Fikrig of Yale University. Fikrig's study was published in the journal Nature on Wednesday. According to the U.S. Centers for Disease Control and Prevention, West Nile virus...

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2008-05-15 11:25:20

Solving the mystery of disease originsBefore West Nile virus arrived in this country, we had (and still have) a home-grown relative of this pathogen. An epidemic of unknown origin exploded around St. Louis, Missouri in the autumn of 1933, a disease that is now known to be transmitted by mosquitoes from birds to people. Now, a new analysis of the genome of St. Louis encephalitis completed at the Sackler Institute for Comparative Genomics at the American Museum of Natural History (AMNH) is...

2008-03-27 13:57:13

Biologists at Purdue University have determined why dengue virus particles undergo structural changes as they mature in host cells and how the changes are critical for enabling the virus to infect new host cells.The findings pertain to all viruses in the family of flaviviruses, which includes a number of dangerous insect-borne diseases such as dengue, West Nile, yellow fever and St. Louis encephalitis. Dengue is prevalent in Southeast Asia, Central America and South America. The virus, which...

2005-09-28 17:03:29

Sept. 28, 2005 "” A monoclonal antibody that can effectively treat mice infected with West Nile virus has an intriguing secret: Contrary to scientists' expectations, it does not block the virus's ability to attach to host cells. Instead, the antibody somehow stops the infectious process at a later point. "This was a complete surprise to us, but it gives us some very useful insights," says senior author Daved Fremont, Ph.D., associate professor of pathology & immunology and of...


Latest Flavivirus Reference Libraries

69_91adf9a2d64d7fdcac1a7b084facc7ac
2011-01-12 16:33:15

Dengue fever and dengue hemorrhagic fever (DHF), caused by the dengue virus, is among the spectrum of acute febrile tropical disease and is transmitted by mosquitoes. Occurring mainly in the tropics it can be life threatening and is caused by four closely related virus stereotypes of the genus Flavivirus. It was identified and named in 1779. It has a nickname of "breakbone fever" due to it causing sever generalized bodyache. It tends to be more prevalent in the urban districts of its range...

0_af221dd1a140204da7f6366df8a69635
2011-01-11 13:44:52

Flavivirus is a genus of the family Flaviviridae. This genus includes the West Nile Virus, Dengue Virus, Tick-borne Encephalitis virus, yellow fever virus, and quite a few others. Flaviviruses get their name from the yellow fever virus. Flavus means yellow in Latin. Yellow fever was named because if caused yellow jaundice in victims. Mosquitoes and ticks transmit these viruses by biting people. Human infections are usually incidental since humans are unable to replicate the virus. Yellow...

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