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Latest Fluoxetine Stories

2011-04-18 21:10:16

An estimated 19 million Americans suffer from depression, and though the symptoms might be recognizable, the brain chemistry that underlies them is incompletely understood. Research suggests that aberrant signaling by a chemical called Brain-Derived Neurotrophic Factor (BDNF) through its receptor TrkB, may contribute to anxiety and depression, and inhibiting this pathway in mice can reduce anxiety and depression-related behaviors. However, translating these findings to clinical studies will...

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2011-04-01 07:40:00

Drug maker GlaxoSmithKline released a new report detailing that its antidepressant Paxil could potentially make people with major depression more likely to become suicidal. But in clinical trials, the company found that attempted suicide rates were relatively low -- 0.34 percent for those using Paxil vs. 0.05 percent for those taking a placebo pill. The report also states that the findings couldn't rule out that the difference was due to chance. "The scientific evidence does not establish...

2011-03-16 14:20:54

Selective serotonin reuptake inhibitors (SSRI) such as Prozac are regularly used to treat severe anxiety and depression. They work by immediately increasing the amount of serotonin in the brain and by causing long term changes in brain function. However it can take weeks of treatment before a patient feels any effect and both beneficial effects and side effects can persist after treatment is stopped. New research published by BioMed Central's open access journal Molecular Brain investigates...

2011-03-14 06:35:00

POINT RICHMOND, Calif., March 14, 2011 /PRNewswire/ -- Transcept Pharmaceuticals, Inc. (Nasdaq: TSPT) today announced the first patient has been enrolled in a Phase 2 clinical study to evaluate TO-2061 as an adjunctive treatment for obsessive compulsive disorder (OCD) in patients who have responded inadequately to currently approved treatments. OCD affects 1 to 2 percent of the United States adult population and can significantly impair the lives of patients and their families....

2011-02-18 17:24:36

The most widely prescribed antidepressants "“ medicines such as Prozac, Lexapro and Paxil "“ work by blocking the serotonin transporter, a brain protein that normally clears away the mood-regulating chemical serotonin. Or so the current thinking goes. That theory about how selective serotonin reuptake inhibitors (SSRIs) work can now be put to the test with a new mouse model developed by neuroscientists at Vanderbilt University. These mice, described in the online edition of the...

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2011-02-08 07:38:20

Berkeley Lab Reports New Fluorescent Assay Reveals TREK1 Mechanism By Lynn Yarris, Berkeley Lab Using a unique and relatively simple cell-based fluorescent assay they developed, scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC), Berkeley have identified a means by which fluoxetine, the active ingredient in Prozac, suppresses the activity of the TREK1 potassium channel. TREK1 activity has been...

2011-02-01 17:14:23

Opiate abuse is a chronic disorder and maintaining abstinence represents a major challenge for addicts. Individuals recovering from opiate dependence have long reported that while the acute withdrawal symptoms from opiates may pass relatively quickly, they do not feel quite right for several weeks or even months thereafter. Called the "protracted abstinence syndrome," this cluster of vague depressive-like symptoms can include reduced concentration, low energy level, poor sleep quality, and...

2010-11-04 08:22:47

(Ivanhoe Newswire) -- An estimated 22.1 percent of Americans ages 18 and older"”about 1 in 5 adults"”suffer from a diagnosable mental disorder. Major depressive disorders affect approximately 5.9 percent of teen females and 4.6 percent of teen males. Unfortunately, major depressive disorders will appear to be cured at first, but the condition recurs in almost half of adolescent patients and more in females, according to this study. "It is associated with functional impairment,...

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2010-11-02 06:45:00

New research from Duke University Medical Center finds that while most depressed adolescents who receive proper treatment appear to recover, the condition recurs in nearly half within five years. Females were at much higher risk of relapse than males, the study found. "We need to learn why females in this age range have higher chances of descending into another major depression after they have made a recovery," said Dr. John Curry, lead author of the study and professor in the Duke Department...

2010-09-16 20:56:25

The response time to antidepressants, such as Prozac, is around three weeks. How can we explain this? The adaptation mechanisms of the neurons to antidepressants has, until now, remained enigmatic. Research, published this week by the teams of Odile Kellermann (Inserm Unit 747 Cellules souches, Signalisation et Prions, Universit© Paris-Descartes) and of Jean-Marie Launay (Inserm Unit 942 Hôpital Lariboisire, Paris and the mental health network, Sant© Mentale),...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'