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Latest Functional Genomics Stories

Researchers Create Initial Catalog Of Human Proteins
2014-05-30 03:12:06

Johns Hopkins Medicine Important resource for speeding research and diagnostic development Striving for the protein equivalent of the Human Genome Project, an international team of researchers has created an initial catalog of the human "proteome," or all of the proteins in the human body. In total, using 30 different human tissues, the team identified proteins encoded by 17,294 genes, which is about 84 percent of all of the genes in the human genome predicted to encode proteins. In...

2013-11-11 11:06:47

Gladstone-led study reveals new insight into origins of our species What does it mean to be human? According to scientists the key lies, ultimately, in the billions of lines of genetic code that comprise the human genome. The problem, however, has been deciphering that code. But now, researchers at the Gladstone Institutes have discovered how the activation of specific stretches of DNA control the development of uniquely human characteristics—and tell an intriguing story about the...

2013-09-16 11:33:23

European scientists, led by researchers from the University of Geneva (UNIGE)'s Faculty of Medicine in the context of the GEUVADIS project, today present a map that points to the genetic causes of differences between people. The study, published in Nature and Nature Biotechnology, offers the largest-ever dataset linking human genomes to gene activity at the level of RNA. Understanding how each person's unique genome makes them more or less susceptible to disease is one of the biggest...

2012-11-07 11:49:14

Scientists have adopted a novel laboratory approach for determining the effect of genetic variation on the efficiency of the biological process that translates a gene's DNA sequence into a protein, such as hemoglobin, according to a presentation, Nov. 6, at the American Society of Human Genetics 2012 meeting in San Francisco. In the 0.1% of the DNA that differs between any two individuals, scientists search for the biological mechanisms underlying human genetic differences, including...

2012-10-09 10:50:36

Findings question earlier studies and shed light on fundamental cellular process Scientists at the Gladstone Institutes have mapped the precise frequency by which genes get turned on across the human genome, providing new insight into the most fundamental of cellular processes–and revealing new clues as to what happens when this process goes awry. In a study being published this week online in the Proceedings of the National Academy of Sciences, Gladstone Investigator Leor...

2011-02-02 07:00:00

ST. LOUIS, Feb. 2, 2011 /PRNewswire/ -- Sigma Life Science, the innovative biological products and services business of Sigma-Aldrich® (Nasdaq: SIAL), today announced that its SAGE Labs initiative has partnered with Cofactor Genomics in an effort to sequence genomes for six of the most widely used strains of rat. As part of the agreement, Cofactor Genomics plans to generate and analyze sequence data using next generation sequencing systems, while SAGE Labs plans to...

2010-11-16 14:00:00

DES MOINES, Iowa and ADELAIDE, Australia, Nov. 16, 2010 /PRNewswire/ -- DuPont and the Australian Centre for Plant Functional Genomics (ACPFG) announced that they have extended their long-standing research collaboration and commitment to increasing productivity in leading production crops. DuPont business Pioneer Hi-Bred and ACPFG partnered in 2005 to discover and develop traits to increase drought tolerance and to decrease the need for soil-applied nitrogen fertilizer, as well as to grow...

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2009-07-07 17:30:00

An international team of scientists has developed salt-tolerant plants using a new type of genetic modification (GM), bringing salt-tolerant cereal crops a step closer to reality.The research team "“ based at the University of Adelaide's Waite Campus in Australia "“ has used a new GM technique to contain salt in parts of the plant where it does less damage.Salinity affects agriculture worldwide, which means the results of this research could impact on world food production and...

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2009-03-05 09:32:49

Scientists across the world are building an extensive repository of genetically modified rice plants in the hope of understanding the function of the approximately 57,000 genes that make up the genome of Oryza sativa. The International Rice Functional Genomics Consortium recently announced the public availability of more than 200,000 rice mutant lines, which represent mutations in about half of the known functional genes mapped for rice to date. * Researchers have estimated the number of...

2008-09-16 18:00:11

ST. LOUIS, Sept. 16 /PRNewswire-FirstCall/ -- Sigma-Aldrich today launched its CompoZr(TM) platform of zinc finger nuclease (ZFN) reagents. The CompoZr ZFN platform of reagents is expected to provide researchers with the ability to target and precisely manipulate the genome of living cells, resulting in cell lines or whole organisms with defined gene deletions, insertions, or corrections. Initially offered as a customized service for developing ZFNs for specific gene targets, the CompoZr...


Word of the Day
callithump
  • A somewhat riotous parade, accompanied with the blowing of tin horns, and other discordant noises; also, a burlesque serenade; a charivari.
'Callithump' is a back-formation of 'callithumpian,' a 'fanciful formation' according to the Oxford English Dictionary. However, the English Dialect Dictionary, says 'Gallithumpians' is a Dorset and Devon word from the 1790s that refers to 'a society of radical social reformers' or 'noisy disturbers of elections and meetings.'
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