Quantcast

Latest Fusion gene Stories

2013-02-11 15:42:02

Nobel Laureate Mario R. Capecchi leads collaboration of researchers Geneticists led by University of Utah Nobel Prize Laureate Mario R. Capecchi, Ph.D., have engineered mice that develop clear cell sarcoma (CCS), a significant step in better understanding how this rare and deadly soft tissue cancer arises. The mouse model also can potentially speed the development of drugs to target genes that must be activated for the cancer to form. CCS arises in connective soft tissues, such as...

2012-06-20 06:21:34

(Ivanhoe Newswire) — A new study opens doors to understanding prostate cancer with the identification of a potential new pathway in prostate cancer cells by which cancer-driving gene products can be created. "Our work shows that cancers have many more tricks than we thought to generate potential cancer-driving genes or gene products," Hui Li, Ph.D., assistant professor of pathology at the University of Virginia in Charlottesville, and a recipient of an Innovative Research Grant from...

2012-06-19 14:07:28

Researchers have identified a potential new pathway in prostate cancer cells by which cancer-driving gene products can be generated, according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research. "Our work shows that cancers have many more tricks than we thought to generate potential cancer-driving genes or gene products," said Hui Li, Ph.D., assistant professor of pathology at the University of Virginia in Charlottesville, and a recipient of...

2012-01-04 06:22:32

(Ivanhoe Newswire) — Smoking is a well-known risk factor for lung cancer, but about 25% of all lung cancer patients have never smoked. According to this study, a gene fusion event could explain a significant proportion of these lung cancer cases, and may serve as a target for new therapies. Recent strides have been made to identify gene mutation events driving cases of lung adenocarcinoma in never-smokers, but the underlying genetic events leading to these lung cancers still remain...

2011-12-23 00:54:36

Smoking is a well-known risk factor for lung cancer, but nearly 25% of all lung cancer patients have never smoked. In a study published online today in Genome Research (www.genome.org), researchers have identified a previously unknown gene fusion event that could explain a significant proportion of lung cancer cases in never-smokers, and might serve as a target for new therapies. Recent strides have been made to identify gene mutation events driving cases of lung adenocarcinoma in...

2011-09-23 07:19:13

(Ivanhoe Newswire) -- Ovarian tumors can be deadly - especially if gone undetected like so many are. A new study, published in the September 20 issue of PLoS Biology, may shed light on how these deadly tumors develop and spread. Stanford researchers, including Patrick O. Brown, senior author of the study and Howard Hughes Medical Institute investigator, were specifically looking for evidence that an ovarian tumor had rearranged its DNA so that two distinct genes were now fused together....

2011-09-21 12:09:55

About 15 percent of cases of an aggressive, difficult-to-detect form of ovarian cancer contain a unique fusion between two neighboring, normally separate genes, say researchers at the Stanford University School of Medicine. Although gene fusions are known to occur in prostate and some blood cancers, they have been notoriously difficult to identify in solid tumors. This is the first recurrent gene fusion found for ovarian cancer. The finding is important because it could give clinicians an...

2011-05-18 13:54:29

About half of prostate cancers have a genetic anomaly that appears to make tumor cells responsive to a new class of cancer-fighting drugs, a new study from the University of Michigan Comprehensive Cancer Center finds. The drugs, called PARP inhibitors, are currently being tested in breast cancer patients with mutations in the BRCA1 and BRCA2 genes, which are found in up to 10 percent of all breast cancers. Half of prostate cancers have a genomic rearrangement that causes the fusion of two...


Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
Related