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Latest Fusion protein Stories

2012-01-06 08:00:00

Company to present data on new designer cell lines metabolically engineered to overcome the specific expression bottlenecks associated with difficult-to-express proteins. Geneva, Switzerland (PRWEB) January 06, 2012 Selexis SA announced today data from the Company´s SUREtechnology Platform will be presented at the 11th Annual PepTalk Conference, January 9-13, 2011 at the Hotel Del Coronado in San Diego, California. Selexis´ chief scientific officer, Pierre-Alain Girod, Ph.D.,...

2011-09-21 12:09:55

About 15 percent of cases of an aggressive, difficult-to-detect form of ovarian cancer contain a unique fusion between two neighboring, normally separate genes, say researchers at the Stanford University School of Medicine. Although gene fusions are known to occur in prostate and some blood cancers, they have been notoriously difficult to identify in solid tumors. This is the first recurrent gene fusion found for ovarian cancer. The finding is important because it could give clinicians an...

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2011-04-23 10:50:00

Research in the worm is shedding light on a protein associated with a number of different human cancers, and may point to a highly targeted way to treat them.University of Wisconsin-Madison scientists were studying a worm protein called TFG-1, which is present in many cell types but whose exact role had never been understood. The scientists discovered that the protein controls key aspects of the movement, or secretion, of growth factors out of cells."TFG-1 has never been implicated in the...

2011-04-20 21:35:00

Rice, Texas A&M labs create protein-patterned fibers Researchers at Rice University and Texas A&M have discovered a way to pattern active proteins into bio-friendly fibers. The "eureka" moment came about because somebody forgot to clean up the lab one night. The new work from the Rice lab of biochemist Kathleen Matthews, in collaboration with former Rice faculty fellow and current Texas A&M assistant professor Sarah Bondos, simplifies the process of making materials with fully...

2011-03-31 22:50:53

Technique could prevent pregnancy in pets, human use is also envisioned Researchers at Weill Cornell Medical College have shown that it is possible to immunize mammals to control fertility. They say their technique could possibly be used on other mammals -- including humans -- because fertility hormones and their receptors are species-non-specific and are similar in both females and males. For pets, the technique could be an alternative to castration and adverse effects of hormone...

2011-01-28 00:12:26

Fusion linked to lymphoma creates powerhouse effect, leads to downstream cancer-causing activity, U-M researchers find What happens when two proteins join together? In this case, they become like a power couple, where the whole is greater than the sum of the parts. API2 and MALT1 are two proteins that become fused together in a subset of lymphomas. The API2 part of the fusion connects with an enzyme called NIK. When it does, MALT1 comes in for the kill, splitting NIK in two, a process called...

2010-07-16 17:32:00

LOS ANGELES, July 16 /PRNewswire/ -- Human erythropoietin (EPO) is a potent neuroprotective agent for multiple brain disorders, including stroke, brain and spinal cord injury, and Parkinson's disease. However, EPO drug development for the brain is limited, because EPO does not cross the blood-brain barrier (BBB). In acute stroke or brain injury, the BBB is intact in the early hours after the insult when neuroprotection is still possible. Therefore, large molecule biopharmaceuticals such as...

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2010-05-20 07:50:00

Antibodies are the immune system's warriors. Their role is to pinpoint disease pathogens, attaching to them and neutralizing their effects. Though antibodies are of great value for biomedical research, the process of creating them has been time-consuming and tedious. Researchers at the Biodesign Institute at Arizona State University have developed a much faster and simpler way of making synthetic antibodies, by carrying out the usual steps in reverse. Stephen Albert Johnston and Chris...

2010-01-07 08:12:00

PRINCETON, N.J., and ATLANTA, Jan. 7 /PRNewswire/ -- Laureate Pharma, Inc., a full-service biopharmaceutical development and protein production company specializing in the development and GMP manufacture of monoclonal antibodies, fusion proteins and other therapeutic protein products, and Iconic Therapeutics, a company focused on the development of treatments for wet adult macular degeneration (wet AMD) and other ophthalmic diseases, today announced the completion of the manufacture of the...

2009-12-14 23:23:35

A new study could point the way to the development of better drugs to fight a deadly form of childhood leukemia called mixed-lineage leukemia (MLL). The study will help researchers in their search for what could be the first highly effective drug for MLL. Such a drug would work by disabling a protein that turns normal blood cells into cancer cells. Researchers from Loyola University Chicago Stritch School of Medicine and the University of Virginia reported results online Dec. 13 in the...


Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
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