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Latest G protein coupled receptors Stories

Skin And Eyes Use Similar Mechanism For Sun Protection
2011-11-04 05:45:22

A group of scientists at Brown University in Rhode Island discovered that the skin and eyes use the same molecular mechanism to protect themselves from the UV light. The discovery was reported in the journal Current Biology. The scientists discovered that the cells that create melanin - melanocytes - contain rhodopsin, a photosensitive receptor used in the eye to detect light. They also discovered that the body produces melanin to protect the cells much quicker than previously suspected....

2011-10-10 09:20:25

New York University biologists have identified a new mechanism for regulating color vision by studying a mutant fly named after Frank ('Ol Blue Eyes) Sinatra. Their findings, which appear in the journal Nature, focus on how the visual system functions in order to preserve the fidelity of color discrimination throughout the life of an organism. They also offer new insights into how genes controlling color detection are turned on and off. Many biologists study how different cells develop to...

2011-09-14 12:18:38

UCLA life scientists have identified for the first time a particular gene's link to optimism, self-esteem and "mastery," the belief that one has control over one's own life – three critical psychological resources for coping well with stress and depression. "I have been looking for this gene for a few years, and it is not the gene I expected," said Shelley E. Taylor, a distinguished professor of psychology at UCLA and senior author of the new research. "I knew there had to be a gene...

2011-08-11 01:00:00

HELSINKI and BERGEN, Norway, August 11, 2011 /PRNewswire/ -- Valkee (http://valkee.com), inventor of the world's first bright-light headset, and scientists from the University of Oulu will present new findings on human brain's photosensitivity at the Scandinavian Physiology Society Annual Meeting 2011, August 12-14. Their research localized the OPN3 protein - known as the light-sensitive photoreceptor protein - in all of the 18 evaluated areas of the brain. These brain...

2011-08-04 12:30:00

SAN DIEGO, Aug. 4, 2011 /PRNewswire/ -- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (J&JPRD) announced today the publication of research that uncovered a previously unknown role for a class of molecules that could lead to future advances in immunologic medicine. The findings show a definitive link between EBI2, a G-protein-coupled receptor that controls B-cell migration, and some unexpected immunological effects of certain oxysterols. Co-authored by the...

2011-07-26 21:10:15

Penn researchers have helped develop a nanotech device that combines carbon nanotubes with olfactory receptor proteins, the cell components in the nose that detect odors. Because olfactory receptors belong to a larger class of proteins that are involved in passing signals through the cell membrane, these devices could have applications beyond odor sensing, such as pharmaceutical research.  The research was led by professor A. T. Charlie Johnson, postdoctoral fellow Brett R. Goldsmith...

2011-07-26 13:57:09

G protein-coupled receptors (GPCRs) are popular drug targets, accounting for about one-third of approved drugs and many hundreds of drugs currently in development. They act as molecular switches that transduce extracellular signals by activating heterotrimeric G proteins (G proteins) located at the inside of the cell. Changes in shape of these proteins determine essential processes, including whether an eye detects light, a virus invades a cell or a drug slows a racing heart. GPCRs sit in the...


Word of the Day
callithump
  • A somewhat riotous parade, accompanied with the blowing of tin horns, and other discordant noises; also, a burlesque serenade; a charivari.
'Callithump' is a back-formation of 'callithumpian,' a 'fanciful formation' according to the Oxford English Dictionary. However, the English Dialect Dictionary, says 'Gallithumpians' is a Dorset and Devon word from the 1790s that refers to 'a society of radical social reformers' or 'noisy disturbers of elections and meetings.'
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