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Latest G protein coupled receptors Stories

2012-02-16 11:19:22

New evidence that receptors for brain's 'reward' chemical provide protection Brain scans of two strains of mice imbibing significant quantities of alcohol reveal serious shrinkage in some brain regions - but only in mice lacking a particular type of receptor for dopamine, the brain's "reward" chemical. The study, conducted at the U.S. Department of Energy's Brookhaven National Laboratory and published in the May 2012 issue of Alcoholism: Clinical and Experimental Research, now online,...

2012-01-26 02:08:43

New research reveals a fascinating and unexpected molecular partnership within the brain neurons that regulate appetite. The study, published by Cell Press in the January 26 issue of the journal Neuron, resolves a paradox regarding a receptor without its hormone and may lead to more specific therapeutic interventions for obesity and disorders of dopamine signaling. Ghrelin is an appetite-stimulating hormone produced by the stomach. Although the ghrelin receptor (GHSR1a) is broadly...

2012-01-19 15:13:40

A receptor found on blood platelets whose importance as a potential pharmaceutical target has long been questioned may in fact be fruitful in drug testing, according to new research from Michigan State University chemists. A team led by Dana Spence of MSU's Department of Chemistry has revealed a way to isolate and test the receptor known as P2X1. By creating a new, simple method to study it after blood is drawn, the team has unlocked a potential new drug target for many diseases that...

2012-01-05 13:06:49

The problem in biology of how to identify the promoters of olfactory receptor genes (>1000 genes) has remained unsolved due to the difficulty of purifying sufficient material from the olfactory epithelium. Researchers at the RIKEN Omics Science Center, collaborating with scientists from Italy, Norway, the United States, the United Kingdom and Germany, have now solved this problem using nanoCAGE technology, which enables comprehensive analysis of transcription start sites (TSSs) from tiny...

2011-12-13 19:09:56

Angewandte Chemie: 3-D structure and hydrogen bridge pattern explained Banana, mango or apricot - telling these smells apart is no problem for the human nose. How the olfactory organ distinguishes such similar smells has been uncovered by an interdisciplinary team of researchers at the RUB. The scientists were the first to shed light on the dynamics of the three-dimensional structure of the binding site of an olfactory receptor. In so doing, they also found a characteristic pattern of...

2011-12-07 22:53:26

The effect of the messenger substance neuropeptide Y depends on the behavior of the mother during infancy Neuropeptide Y (NPY) is the most abundant peptide hormone of the central nervous system. It is involved in various processes including stress management, the development of anxiety behavior and body weight regulation. A collaborative research group including scientists from the Max Planck Institute for Medical Research in Heidelberg has demonstrated using mice that intensive maternal...

2011-12-07 14:27:11

Long the bane of picky eaters everywhere, broccoli´s taste is not just a matter of having a cultured palate; some people can easily taste a bitter compound in the vegetable that others have difficulty detecting. Now a team of Penn researchers has helped uncover the evolutionary history of one of the genes responsible for this trait. Beyond showing the ancient origins of the gene, the researchers discovered something unexpected: something other than taste must have driven its evolution....


Word of the Day
lunula
  • A small crescent-shaped structure or marking, especially the white area at the base of a fingernail that resembles a half-moon.
This word is a diminutive of the Latin 'luna,' moon.
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