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Latest G proteins Stories

2013-10-21 10:08:34

Patients with cancers driven by the protein KRAS, which are particularly hard to treat, may benefit from small molecules that attach to and disrupt the function of a KRAS-containing protein complex, according to results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19-23. Mutant forms of the protein KRAS are found in approximately 30 percent of all cancers. They are responsible for many of the hallmarks of these...

2013-03-14 16:56:01

First-in-class chemical compound might control metastases It´s the spread of the original cancer tumor that kills most people. That´s why cancer researchers vigorously search for drugs that can prevent metastases, the spread of cancer. The research team co-led by Angela Wandinger-Ness, PhD, and Larry Sklar, PhD, at the University of New Mexico Cancer Center has found a chemical compound that appears to control cell migration and adhesion, two important characteristics of...

2012-05-10 23:00:47

The human body does a great job of generating new cells to replace dead ones but it is not perfect. Cells need to communicate with or signal to each other to decide when to generate new cells. Communication or signaling errors in cells lead to uncontrolled cell growth and are the basis of many cancers. At The University of Texas Health Science Center at Houston (UTHealth) Medical School, scientists have made a key discovery in cell signaling that is relevant to the fight against melanoma...

2011-11-10 08:00:00

The EurekaMag Science Magazine has just been featured on a video available at the website's homepage and at YouTube. It has also published a new review on RhoA (ras homolog gene family, member A) which is a GTPase protein regulating a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. (PRWEB) November 10, 2011 The Video on EurekaMag.com which has just been uploaded to YouTube focuses on the website's vast library of...

2011-04-21 14:37:16

Key finding has the potential to improve crops' response to drought, disease and other stresses The most elaborate heterotrimeric G-protein network known to date in the plant kingdom has been identified by Dr. Sona Pandey, principal investigator at the Danforth Plant Science Center.  The results of this research are published in the recent article, "An elaborate heterotirmeric G-protein family from soybean expands the diversity of G-protein networks," in the New Phytologist. G-proteins...

2011-01-18 22:52:55

The Ras oncogene "“ frequently mutated in cancers "“ was once thought to act at the outermost region of the cell called the plasma membrane. However, researchers at Baylor College of Medicine demonstrated first in yeast and now in mammalian cells that the Ras protein also has activity in the interior of the cell called the cytoplasm, and that its effectiveness in cancer causation depends on where it is. "In this study, we wanted to know if the cytoplasmic Ras pathway can be found...

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2008-10-25 11:33:05

Molecular switch shared by humans may also help immune cells locate infection sites Amoebas glide toward their prey with the help of a protein switch that controls a molecular compass, biologists at the University of California, San Diego have discovered. Their finding, detailed in this week's issue of the journal Current Biology, is important because the same molecular switch is shared by humans and other vertebrates to help immune cells locate the sites of infections. The amoeba...

2005-08-08 17:37:49

CHAPEL HILL -- Scientists from the University of North Carolina at Chapel Hill School of Medicine and the UNC Lineberger Comprehensive Cancer Center have identified a protein that may inhibit cellular movement, or migration. The protein, CIB1, or calcium and integrin-binding protein 1, was originally discovered at UNC in 1997 as a blood platelet protein that may play a role in clotting. Cell migration belongs to the most rudimentary of cellular functions that allow processes such as fetal...


Word of the Day
bodacious
  • Remarkable; prodigious.
  • Audacious; gutsy.
  • Completely; extremely.
  • Audaciously; boldly.
  • Impressively great in size; enormous; extraordinary.
This word is probably from the dialectal 'boldacious,' a blend of 'bold' and 'audacious.'
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