Latest G-quadruplex Stories
On the 60th anniversary of the publication of the paper describing the double-helix structure of DNA, researchers from Cambridge University reportedly have proven the existence of four-stranded “quadruple helix” DNA structures within the human genome.
Designers of anti-cancer drugs are aiming their arrows at mysterious chunks of the genetic material DNA that may play a key role in preventing the growth and spread of cancer cells, according to an article in the current issue of Chemical & Engineering News, ACS' weekly newsmagazine.
The natural world is a shining example when it comes to the self-assembly of molecules. However, it has not disclosed all of its secrets yet. Controlling the shape and structure of self-assembled systems continues to be a stumbling block for scientists.
By Haider, Shozeb Parkinson, Gary N; Neidle, Stephen ABSTRACT Guanine-rich DNA repeat sequences located at the terminal ends of chromosomal DNA can fold in a sequence-dependent manner into G-quadruplex structures, notably the terminal 150-200 nucleotides at the 3' end, which occur as a single-stranded DNA overhang.