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Latest G-quadruplex Stories

Human Genome Found To Contain Quadruple Helix DNA Strands
2013-01-21 05:09:41

redOrbit Staff & Wire Reports - Your Universe Online On the 60th anniversary of the publication of the paper describing the double-helix structure of DNA, researchers from Cambridge University reportedly have proven the existence of four-stranded “quadruple helix” DNA structures within the human genome. It was in 1953 that James D. Watson and Francis Crick, also of Cambridge University, published a paper which described the interweaving structure of the double-stranded...

2009-11-04 14:15:13

Designers of anti-cancer drugs are aiming their arrows at mysterious chunks of the genetic material DNA that may play a key role in preventing the growth and spread of cancer cells, according to an article in the current issue of Chemical & Engineering News, ACS' weekly newsmagazine. C&EN Deputy Assistant Managing Editor Stu Borman notes that the DNA structures, which scientists term "quadruplexes" because they have four-sided structures, are a genre of folded DNA that may help...

2009-05-14 15:27:08

The natural world is a shining example when it comes to the self-assembly of molecules. However, it has not disclosed all of its secrets yet. Controlling the shape and structure of self-assembled systems continues to be a stumbling block for scientists. Yet such structures, in which the different molecules cooperate with each other, can have unrivalled characteristics. Self-assembly could provide the way forward for the future mass production of nanomaterials, nanodrugs and...

2008-08-22 03:00:15

By Haider, Shozeb Parkinson, Gary N; Neidle, Stephen ABSTRACT Guanine-rich DNA repeat sequences located at the terminal ends of chromosomal DNA can fold in a sequence-dependent manner into G-quadruplex structures, notably the terminal 150-200 nucleotides at the 3' end, which occur as a single-stranded DNA overhang. The crystal structures of quadruplexes with two and four human telomeric repeats show an all-parallel-stranded topology that is readily capable of forming extended stacks of such...


Word of the Day
bellycheer
  • Good cheer; viands.
  • To revel; to feast.
The word 'bellycheer' may come from 'belle cheer', "good cheer".
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