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Latest Gamma-Aminobutyric acid Stories

Propofol Controlled With Light, Possible Blindness Help As Well
2012-09-14 08:58:36

Connie K. Ho for redOrbit.com — Your Universe Online A new study by German researchers found that a light-sensitive element that was mixed with the anesthetic propofol was able to be managed by light and the mixture could possibly be used to treat particular eye disorders. To begin, the scientists believe that inhibitory neurotransmitters can limit the activity of neurons and this reduction effect acts as the foundation for different anesthetics. In particular, propofol can work...

New Model Synapse Could Help With Disorders Such As Epilepsy And Anxiety
2012-08-08 09:42:42

A new way to study the role of a critical neurotransmitter in disorders such as epilepsy, anxiety, insomnia, depression, schizophrenia, and alcohol addiction has been developed by a group of scientists led by Gong Chen, an associate professor of biology at Penn State University. The new method involves molecularly engineering a model synapse -- a structure through which a nerve cell sends signals to another cell. This model synapse can precisely control a variety of receptors for the...

2012-08-07 09:45:45

Studies in mice reveal how mood-altering drugs may affect brain stem cells Working with mice, Johns Hopkins researchers say they have figured out how stem cells found in a part of the brain responsible for learning, memory and mood regulation decide to remain dormant or create new brain cells. Apparently, the stem cells “listen in” on the chemical communication among nearby neurons to get an idea about what is stressing the system and when they need to act. The researchers...

2012-06-18 11:01:12

Researchers at Baylor College of Medicine and Texas Children's Hospital have identified commensal bacteria in the human intestine that produce a neurotransmitter that may play a role in preventing or treating inflammatory bowel diseases such as Crohn's disease. "We identified, to our knowledge, the first bifidobacterial strain, Bifidobacterium dentium, that is capable of secreting large amounts of gamma-aminobutyric acid (GABA). This molecule is a major inhibitory neurotransmitter in the...

2012-05-15 22:28:31

A novel mechanism for anxiety behaviors, including a previously unrecognized inhibitory brain signal, may inspire new strategies for treating psychiatric disorders, University of Chicago researchers report. By testing the controversial role of a gene called Glo1 in anxiety, scientists uncovered a new inhibitory factor in the brain: the metabolic by-product methylglyoxal. The system offers a tantalizing new target for drugs designed to treat conditions such as anxiety disorder, epilepsy,...

2012-03-21 05:45:11

(Ivanhoe Newswire)-- Huntington's disease is a dreaded and debilitating congenital neurological disorder. There are little successful treatments and no cure. But a special type of brain cell forged from stem cells could help restore the muscle coordination deficits that cause the uncontrollable spasms characteristic of the disease. "This is really something unexpected," Su-Chun Zhang, a University of Wisconsin-Madison neuroscientist and the senior author of the new study, was quoted...

2012-03-15 23:39:45

Huntington's disease, the debilitating congenital neurological disorder that progressively robs patients of muscle coordination and cognitive ability, is a condition without effective treatment, a slow death sentence. But if researchers can build on new research reported this week (March 15, 2012) in the journal Cell Stem Cell, a special type of brain cell forged from stem cells could help restore the muscle coordination deficits that cause the uncontrollable spasms characteristic of the...

2012-01-18 21:25:35

New research shows how neurons interact and could lead to new treatment for addiction Harvard scientists have developed the fullest picture yet of how neurons in the brain interact to reinforce behaviors ranging from learning to drug use, a finding that might open the door to possible breakthroughs in the treatment of addiction. The finding is the result of a year-long effort by a team of researchers led by associate professor of Molecular and Cellular Biology Naoshige Uchida to examine...

2012-01-04 08:56:59

Quite early in its development, the mammalian brain has all the raw materials on hand to forge complex neural networks. But forming the connections that make these intricate networks so exquisitely functional is a process that occurs one synapse at a time. An important question for neuroscience has been: how exactly do stable synapses form? How do nerve cells of particular types know which of their cortical neighbors to "synapse" with, and which to leave out of their emerging networks?...

2011-11-04 20:52:12

Impulsive individuals tend to display aggressive behavior and have challenges ranging from drug and alcohol abuse, to problem gambling and difficult relationships. They are less able to adapt to different social situations. Impulsivity is also a common feature of psychiatric disorders. New research in Biological Psychiatry shows that people may react this way, in part, because they have lower levels of GABA (gamma-aminobutyric acid), the most important inhibitory neurotransmitter, in a...