Latest Gamma-Aminobutyric acid Stories

2009-09-10 06:57:14

Immature cortical neurotransmitter response underlies invisible seizures, blocks response to antiseizure drug A study led by MassGeneral Hospital for Children (MGHfC) investigators is providing new insight into the mechanism of neonatal seizures, which have features very different from seizures in older children and adults. In their report in the Sept. 10 issue of Neuron, the researchers describe finding how neurons in different parts of the brains of newborn mammals respond differently to...

2009-08-31 07:37:00

CORAL GABLES, Fla., Aug. 31 /PRNewswire-FirstCall/ -- Catalyst Pharmaceutical Partners, Inc. (Nasdaq: CPRX) announced today that the Company executed a license agreement under which it acquired exclusive worldwide rights to commercialize novel GABA aminotransferase inhibitors and derivatives of vigabatrin discovered by Northwestern University. These compounds may have applications to a broad range of neurological diseases, including addiction and epilepsy. Catalyst intends to pursue...

2009-05-21 13:05:16

British scientists say studying the way a person's brain sings could improve our understanding of conditions such as epilepsy and schizophrenia. Researchers in Cardiff University's Brain Research Imaging Center say they've discovered a person's brain produces a unique electrical oscillation at a particular frequency when a person looks at a visual pattern. That frequency of oscillation, the scientists said, appears to be determined by the concentration of a neurotransmitter chemical, GABA in...

2009-05-19 09:58:44

Studying the way a person's brain 'sings' could improve our understanding of conditions such as epilepsy and schizophrenia and help develop better treatments, scientists at Cardiff University have discovered. Research by a team working in Cardiff University's Brain Research Imaging Centre (CUBRIC) has discovered that a person's brain produces a unique electrical oscillation at a particular frequency when a person looks at a visual pattern. Importantly, the team found that the frequency of...

2008-12-12 10:01:00

A large proteomics study on the brains of newborn mice provides more evidence that numbing drugs often used in obstetric or pediatric medicine can have profound and long-term negative effects, even after minimal exposure.This study, appearing in the December issue of Molecular and Cellular Proteomics, highlights the delicate state of the developing nervous system and reinforces the use of caution when administering sedatives, anesthetics, and anti-convulsants to pregnant women or...

2008-11-27 09:50:41

In a novel study appearing this week in Neuron, Brandeis researchers identify for the first time a specific set of wake-promoting neurons in fruit flies that are analogous to cells in the much more complex sleep circuit in humans. The study demonstrates that in flies, as in mammals, the sleep circuit is intimately linked to the circadian clock and that the brain's strategies to govern sleep are evolutionarily ancient. In the study, researchers quieted ventral lateral neurons (LNvs) and...

2008-07-28 03:00:38

Addex Pharmaceuticals (SWX: ADXN) released today financial results for the first half of 2008 and gave an update on the status of its lead product, ADX10059, which is in development for GERD (gastroesophageal reflux disease) and migraine. Financial Highlights * 1H08 net profit: CHF2.6 million * 1H08 revenues: CHF25.8 million * Cash and cash equivalents at June 30, 2008: CHF142.8 million * Addex reiterates 2008 full year cash burn guidance of CHF25-30 million Pipeline &...

2008-01-09 15:00:00

Research and Markets (http://www.researchandmarkets.com/reports/c78985) has announced the addition of Pipeline Report - Neuronal Alpha 7 Nicotinic Receptors: Candidates for the Treatment of Alzheimers Disease and Schizophrenia to their offering. Neuronal alpha 7 nicotinic receptor (a7nAChR) ligands represent an emerging class of drug for the treatment of various CNS disorders associated with cognitive dysfunction. This report describes the proof of concept supporting the development of this...

2005-08-04 16:05:25

Durham, N.C. "“ Using a novel analysis of the interactions among related genes, Duke University Medical Center researchers have uncovered some of the first evidence that complex genetic interactions account for autism risk. The Duke team found that the brain mechanism that normally stops or slows nerve impulses contributes to the disease. The team's findings implicate the so-called GABA receptor genes, which are genes that code for key components of "off switches" in the brain's...

Word of the Day
  • A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
  • A gentle breeze; a waft; a breath.
  • Any rumor that engages general attention.
  • A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
  • To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
  • To breathe in or as in sleep.
  • To utter in a whining or monotonous tone.
According to the OED, from the 16th century, this word is 'almost exclusively Scots and northern dialect until adopted in general literary use in the 19th.'