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Last updated on April 20, 2014 at 8:28 EDT

Latest Gastrin Stories

2013-07-15 23:23:29

Cancer Advances, Inc. (Cancer Advances), a wholly owned, biotechnology portfolio company of Cato BioVentures, announces the allowance of a new patent. The newly released patent covers monoclonal antibodies to the gastrin hormone and has been allowed in Canada. Durham, North Carolina (PRWEB) July 15, 2013 Cancer Advances, Inc. (Cancer Advances), a wholly owned, biotechnology portfolio company of Cato BioVentures, announces the allowance of a new patent. The newly released patent covers...

2012-06-06 06:26:33

BOSTON, June 6, 2012 /PRNewswire/ -- Rhythm announced today the initiation of a Phase 2 clinical trial for RM-131, the company's novel ghrelin agonist, for the treatment of gastroparesis in patients with Type I and Type II diabetes. Ghrelin is a peptide hormone produced in the stomach that stimulates gastric motility. "We are excited about the clinical profile of RM-131 as we bring it forward into Phase 2 development," said Liz Stoner, MD, Chief Development Officer of Rhythm. "Extensive...

2011-05-09 07:00:00

BOSTON, May 9, 2011 /PRNewswire/ -- Rhythm announced today results demonstrating that RM-131, the company's novel ghrelin agonist, was highly effective in restoring normal gastric function in animal models of delayed gastric emptying owing to a direct prokinetic effect. The results were the subject of an oral presentation by Lee M. Kaplan, MD, PhD (Massachusetts General Hospital, Harvard Medical School) titled "RM-131: A Potent Gastroprokinetic Agent" at the Digestive Disease Week 2011...

2010-06-08 12:14:22

Study indicates reduced muscle tone in the esophagus may cause acid reflux disease, a digestive disorder of the stomach and esophagus Molecular imaging has uncovered what may be to blame for acid reflux disease, a painful and potentially dangerous illness that affects a sizeable percentage of the population. A study presented at SNM's 57th Annual Meeting provides further evidence that the disease of the digestive system is brought on by a lack of tone, or motility, in the esophageal muscles...

2010-05-05 08:00:00

NEW ORLEANS, May 5 /PRNewswire/ -- What: Data results from a recent retrospective analysis of DEXILANT delayed release capsules and lansoprazole were presented at Digestive Disease Week (DDW) 2010 in New Orleans. DEXILANT is a proton pump inhibitor (PPI) with a Dual Delayed Release(TM) (DDR) formulation. Takeda recently announced that the product trade name for dexlansoprazole in the United States would be changed to DEXILANT from KAPIDEX(TM) (dexlansoprazole). The medical community...

2010-03-30 14:17:48

Gastroesophageal reflux disease (GERD) is an important public health problem which is extremely common nowadays. Symptoms of GERD arise from the exposure of increased acid gastric contents into the lower part of the esophageal mucosa. Most patients with GERD have NERD with invisible mucosal damages under endoscopy. There is not a gold standard to diagnose NERD due to the poor sensitivity, specificity, and reproducibility of many existing methods. Dilated intercellular spaces (DIS) in the...

2010-02-17 07:00:00

INDIANAPOLIS, Feb. 17 /PRNewswire/ -- Marcadia Biotech Inc. today announced that it has initiated a Phase 1 clinical trial of MAR701, a novel dual agonist of the incretin hormone receptors for glucagon-like peptide-1 (GLP-1) and gastric inhibitory peptide (GIP). Marcadia plans to initially develop this compound as a treatment for type 2 diabetes with once-weekly dosing. The Phase 1 trial will evaluate MAR701 in healthy volunteers at escalating dose levels. MAR701 targets two peptide...

2009-07-21 14:50:42

A new DNA vaccine inhibited malignant melanoma, a deadly form of skin cancer, in mice by eliciting antibodies that target a gastrin-releasing peptide which is known to play a key role in cancer development. The researchers from China and the U.S. report their findings in the July 2009 issue of the journal Clinical and Vaccine Immunology.Gastrin-releasing peptide (GRP) is an important human peptide that regulates gastric acid secretion and motor function as well as elicits gastrin release....

2009-06-29 10:23:13

U.S. scientists say they've determined both an overabundance and a lack of the hormone gastrin play key rolls in bacterial-induced stomach cancer. More than 50 percent of the world's population is infected with Helicobacter pylori, which is strongly linked to the development of gastric ulcers and stomach cancer, researchers said. Helicobacter infection results in increased expression of gastrin, a hormone that stimulates secretion of gastric acid, However, the role of gastrin in cancer...

2009-06-24 15:34:26

A group led by Columbia University Medical Center's Timothy Wang, M.D., has studied the role of Helicobacter infection in the development of stomach cancer and found that the hormone gastrin, which stimulates secretion of gastric acid, plays a key role in the development of Helicobacter-induced stomach cancer, and may have distinct effects on carcinogenesis in different parts of the stomach.More than 50 percent of the world's population is infected with Helicobacter, which causes chronic...


Latest Gastrin Reference Libraries

Stomach
2013-03-04 14:34:35

The stomach is the hollow organ that helps along digestion after mastication (chewing). It is the next step after the esophagus and before the small intestines. Formation and Orientation The stomach is composed of four parts. The cardia is the first part of the stomach in the digestive tract. It is the part of the stomach that allows the food to empty from the esophagus. The most northern part of the stomach is the Fundus. This section is the part that creates the curved part of the...

Gastric Chief Cell
2012-07-01 18:59:43

The Gastric Chief Cell (peptic cell or gastric zymogenic cell) is a cell found in the stomach that releases pepsinogen, gastric lipase and Chymosin (an enzyme that clots milk). Pepsinogen is only released when the cell is stimulated by a number of factors, including cholinergic activity and increased acidity in the stomach. The gastric chief cell works in conjunction with the parietal cell, which releases gastric acid, converting pepsinogen into pepsin. The term “chief cell” is...

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