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Latest gastroparesis Stories

2008-09-09 03:00:26

AGI Therapeutics Interim financial results for the six months ended 30 June 2008 -- ARDIS-1 now 75% enrolled -- Dublin, Ireland, 9 September 2008 - AGI Therapeutics plc ("AGI" or the"Company") (AIM, IEX: AGI), a speciality pharmaceutical development company focused on gastrointestinal drug products, today reports interim financial results for the six months ended 30 June 2008. The Company also announces that enrolment into ARDIS-1, the first of two...

2008-07-22 06:00:17

Tranzyme Pharma, a leading biopharmaceutical company developing novel mechanism-based therapeutics for the treatment of gastrointestinal (GI) and metabolic disorders, announced today that the Company has received Notices of Allowance from the U.S. Patent and Trademark Office (USPTO) for two patent applications entitled "Macrocyclic Modulators of the Ghrelin Receptor" and "Spatially-Defined Macrocyclic Compounds Useful for Drug Discovery". Together, the patents expected to be issued based...

2008-07-01 09:00:13

Elixir Pharmaceuticals, Inc., today announced the Company has entered an exclusive license agreement with Boston University to key intellectual property covering discoveries regarding the use of modulators of SIRT1, a member of the sirtuin class of protein deacetylase enzymes. SIRT1 is the human equivalent of Sir2, a gene identified in yeast that has been recognized to play a key role in the control of lifespan, metabolism, resistance to stress and other cellular regulatory pathways. The...

2008-06-23 06:00:06

Tranzyme Pharma announces the successful results from a "Thorough QT/QTc" study of the company's lead product TZP-101, an intravenous gastrointestinal prokinetic agent currently in two Phase IIb trials for the treatment of postoperative ileus (POI) and severe gastroparesis. The study, required by the US Food and Drug Administration (FDA) for all new chemical entities, was conducted to evaluate the cardiac safety of TZP-101, with a focus on cardiac repolarization as measured by the...

2008-06-18 09:00:09

Elixir Pharmaceuticals, Inc., today announced that results from in-vivo preclinical studies with the Company's ghrelin agonist, EX-1314, were presented at the annual meeting of the Endocrine Society. EX-1314 is expected to enter human clinical testing this year. This new compound has been the subject of extensive preclinical development, and these new data provide the first demonstrations that an orally active, small molecule ghrelin agonist can enhance gastrointestinal motility. Elixir will...

2008-06-17 06:00:07

Tranzyme Pharma announced today the successful completion of a Phase I, placebo-controlled, single ascending dose study of its orally administered ghrelin agonist, TZP-102. TZP-102 is the second drug candidate from Tranzyme's internal R&D efforts to reach clinical development. It is a potent prokinetic agent initially being developed for the treatment of mild-to-moderate gastroparesis. The Phase I study showed that TZP-102 has excellent oral bioavailability in man and is safe and...


Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
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