Quantcast

Latest GDNF family of ligands Stories

2013-04-18 21:50:25

Amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, is a fatal disease that causes motor neurons, which are responsible for controlling muscles, to die. A study published by Cell Press on April 18th in Cell Stem Cell has revealed a novel stem-cell-based approach to screen for effective treatments, which are sorely lacking. Applying this method to motor neurons derived from stem cells taken from an ALS mouse model and human patients, the researchers discovered a promising...

2009-09-23 16:22:00

NEW YORK, Sept. 23 /PRNewswire-USNewswire/ -- The Michael J. Fox Foundation has committed up to $5 million for research to successfully translate neurotrophic factor advances from pre-clinical and early-phase clinical work into a practical, patient-relevant treatment for Parkinson's disease. The funding will be awarded under a new Directed LEAPS (Linked Efforts to Accelerate Parkinson's Solutions) initiative. The Foundation's intention is to identify and drive ambitious projects with a...

2009-03-25 08:11:06

 A growth factor used in clinical experiments to rescue dying brain cells in Parkinson patients may cause unwanted weight loss if delivered to specific areas of the brain, according to University of Florida researchers in the March online edition of Molecular Therapy.The discovery is a cautionary warning for experimental treatments to treat Parkinson's disease that use GDNF, short for glial cell line-derived neurotrophic factor.In addition, the finding broadens understanding of the...

2005-12-27 14:16:16

NEW YORK (Reuters Health) - Genetically modified nerve 'progenitor' cells can be used as mini-pumps to deliver nerve growth factor to the brain, a new study in animals shows. The results suggest such an approach could be used to treat Parkinson's disease and other brain diseases in humans, Dr. Clive D. Svendsen of the University of Wisconsin-Madison and colleagues report. A nerve growth factor called "glial cell line-derived neurotrophic factor" (abbreviated to GDNF) has been shown...

2005-07-03 16:55:00

Analysis of the brain of a patient suffering from Parkinson's Disease has shown that the experimental treatment he received caused regrowth of the nerve fibres that are lost in this disease. The findings are reported in the July issue of Nature Medicine. This is the first time that any treatment has been shown to reverse the loss of nerve fibres in Parkinson's Disease. The 62-year-old man was one of five patients in a pilot study carried out by Mr Steven Gill at Frenchay Hospital in...


Word of the Day
cenobite
  • One of a religious order living in a convent or in community; a monk: opposed to anchoret or hermit (one who lives in solitude).
  • A social bee.
This word comes from the Latin 'coenobium,' convent, which comes from the Greek 'koinobios,' living in community.
Related