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Latest Geldanamycin Stories

2012-01-24 06:31:09

(Ivanhoe Newswire) -- The American Cancer Society estimates there will be more than 200,000 new cases of invasive breast cancer in women and 39,000 deaths, this year alone. Other than skin cancer, breast cancer is the most common form of cancer for women in the United States. Any hope about how to fight these two cancers is highly useful. Now, two studies have shown that targeting a single protein can help fight both breast cancer and leukemia. Hsp90 is a specialized chaperone that assists...

2011-12-02 12:41:50

New research reports on new method that reveals complete set of aberrant signaling pathways that give rise to cancers One major obstacle in the fight against cancer is that anticancer drugs often affect normal cells in addition to tumor cells, resulting in significant side effects. Yet research into development of less harmful treatments geared toward the targeting of specific cancer-causing mechanisms is hampered by lack of knowledge of the molecular pathways that drive cancers in...

2011-06-29 12:16:54

Finding could lead to new and improved drugs for several types of cancer Most of us have had a doctor prescribe an antibiotic for a stubborn bacterial infection, or for a cut that gets infected.  However, prescribing an antibiotic to fight cancer?  In fact, anti-cancer antibiotics have been used since the 1950s to successfully treat several forms of cancer, but often the side effects limit the duration they can be given to a patient. One particularly promising anti-cancer...

2011-05-19 12:59:00

NEW YORK, May 19, 2011 /PRNewswire/ -- NexGenix Pharmaceuticals Inc., a privately-held company developing treatments for cancer, neurodegenerative diseases, and orphan neurogenetic disorders, today announced that the United States Patent and Trademark Office (USPTO) has issued a Notice of Allowance for a key patent for a platform of Hsp90 inhibitors based on derivatives of the naturally occurring pochonin family, Pochonia chlamydospora. The platform of fully synthetic small molecules...

2008-10-23 12:00:26

Infinity Pharmaceuticals, a cancer drug discovery and development company, has announced preclinical data demonstrating anti-tumor activity with IPI-493, the company's oral heat shock protein 90 inhibitor. In preclinical studies, IPI-493 potently inhibits heat shock protein 90 (Hsp90) and has strong pharmaceutical properties in vitro and in vivo, including selectivity for cancer cells over normal cells, as well as high oral bioavailability, the company said. Moreover, IPI-493 showed...

2005-11-29 13:45:32

CHAPEL HILL "“ University of North Carolina at Chapel Hill scientists have identified a molecule that stimulates the aggressive growth of prostate cancer. The molecule, Ack1, a member of the growth-promoting tyrosine kinase gene family, stimulates tumor formation in part by signaling prostate cells to rid themselves of a tumor-suppressor protein. Normally, this suppressor protein would inhibit rapid cell growth by signaling the cell to destroy itself. A report on the study, which...


Word of the Day
jument
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.
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