Latest gene amplification Stories

2013-05-08 17:53:05

An international group of investigators, led by researchers at Thomas Jefferson University's Kimmel Cancer Center, have solved the mystery of why a substantial percentage of castrate-resistant metastatic prostate cancer cells contain abnormally high levels of the pro-growth protein Stat5. They discovered that the gene that makes the protein is amplified – duplicated many times over – in these cancer cells, which allows them to produce excess amounts of the oncogenic protein....

2011-11-04 12:00:00

Current testing protocols for HER2 amplification may exclude thousands of patients who actually have HER2 gene amplification, delaying or preventing them from receiving potentially life-saving treatment. A new laboratory testing protocol can more accurately identify an important group of breast cancer patients who are most likely to benefit from a âœtargeted therapyâ shown to dramatically improve survival. This recent discovery by PhenoPath Laboratories...

2010-01-18 15:49:00

BOULDER, Colo., Jan. 18 /PRNewswire-USNewswire/ -- A new study entitled "Gene amplification confers glyphosate resistance in Amaranthus palmeri" from a research team including Monsanto scientists Dafu Wang and Douglas Sammons echoes conclusions from The Organic Center (TOC) report "Impacts of Genetically Engineered Crops on Pesticide Use in the United States: The First Thirteen Years." Published in Proceedings of National Academy of Sciences (PNAS) in December 2009, the Monsanto-funded...

2008-06-14 03:00:00

By Hicks, David G Kulkarni, Swati * Context.-Overexpression of human epidermal growth factor receptor 2 (HER2) is an adverse prognostic parameter for patients with breast cancer. Patients with HER2- positive tumors are, however, likely to gain significant benefit from targeted therapy with trastuzumab. Four largescale trials have assessed the efficacy and safety of adjuvant trastuzumab. In all 4 trials, disease-free survival and overall survival were significantly improved with adjuvant...

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