Quantcast

Latest Gene duplication Stories

2011-10-05 12:25:09

When cells divide normally, DNA gets copied perfectly and distributed among the daughter cells with an even hand. Occasionally though, DNA breaks during division and is rearranged, resulting in duplications or deletions of important parts of the blueprint. Now researchers at Baylor College of Medicine who study families with such genomic disorders have found a shared, yet unusual, architecture resulting from this jumble that is associated with very severe forms of disease. They also...

2011-10-05 05:53:07

(Ivanhoe Newswire) — Autism is one of the most common genetic alterations, caused by a deletion of the 27-gene cluster on chromosome 16. By generating mouse models of autism, scientists at Cold Spring Harbor Laboratory (CSHL) provided the first evidence that inheriting fewer copies of these genes leads to features resembling those used to diagnose children with autism. "Children normally inherit one copy of a gene from each parent. We had the tools to see whether copy number changes...

Evidence Found For Genetic Basis Of Autism
2011-10-04 04:32:58

[ Watch the Video ] Models of autism show that gene copy number controls brain structure and behavior Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered that one of the most common genetic alterations in autism -- deletion of a 27-gene cluster on chromosome 16 -- causes autism-like features. By generating mouse models of autism using a technique known as chromosome engineering, CSHL Professor Alea Mills and colleagues provide the first functional evidence that inheriting...

2011-10-03 15:45:04

When cells divide normally, DNA gets copied perfectly and distributed among the daughter cells with an even hand. Occasionally though, DNA breaks during division and is rearranged, resulting in duplications or deletions of important parts of the blueprint. Now researchers at Baylor College of Medicine who study families with such genomic disorders have found a shared, yet unusual, architecture resulting from this jumble that is associated with very severe forms of disease. They also...

2011-09-19 05:26:08

(Ivanhoe Newswire) -- A chromosomal "catastrophe" that occurs early in development may be to blame for some cases of developmental delay or cognitive disorders, according to new research. Investigators from Baylor College of Medicine analyzed the DNA of 17 patients who were referred to their center because of unexplained developmental problems. "Four were very complex," Dr. Pengfei Liu, a graduate student at BCM, was quoted as saying. "One had 18 rearrangements in one chromosome. It was...

2011-09-16 11:13:29

Using a diversity of DNA sequencing and human genome analytic techniques, researchers led by Baylor College of Medicine have identified some cases of developmental delay or cognitive disorders associated with a sudden chromosomal catastrophe that occurred early in development, perhaps during cell division when DNA is replicated. In a report in the journal Cell, Dr. Weimin Bi, assistant professor of molecular and human genetics, Dr. James R.Lupski, vice chair of molecular and human...

2011-09-15 13:05:47

Using a diversity of DNA sequencing and human genome analytic techniques, researchers led by Baylor College of Medicine have identified some cases of developmental delay or cognitive disorders associated with a sudden chromosomal catastrophe that occurred early in development, perhaps during cell division when DNA is replicated. In a report in the journal Cell, Dr. Weimin Bi, assistant professor of molecular and human genetics, Dr. James R.Lupski, vice chair of molecular and human...

2011-09-15 05:14:56

(Ivanhoe Newswire) -- A chromosomal "catastrophe" that occurs early in development may be to blame for some cases of developmental delay or cognitive disorders, according to new research. Investigators from Baylor College of Medicine analyzed the DNA of 17 patients who were referred to their center because of unexplained developmental problems. "Four were very complex," Dr. Pengfei Liu, a graduate student at BCM, was quoted as saying. "One had 18 rearrangements in one chromosome. It was...

Genetic Cause Of Extreme Thinness Identified
2011-09-01 05:19:22

  People with surplus copies of certain genes are much more prone to extreme thinness, as well as a syndrome in children known as "failure to thrive," according to a study published Thursday in the journal Nature. One in 2,000 people have part of their chromosome 16 duplicated, with men 23 times and women five times more likely to be seriously underweight in these cases, the researchers found. A person typically inherits a copy of each chromosome from each parent, giving us two...

2011-08-31 23:18:40

Scientists have discovered a genetic cause of extreme thinness for the first time, in a study published today in the journal Nature. The research shows that people with extra copies of certain genes are much more likely to be very skinny. In one in 2000 people, part of chromosome 16 is duplicated, making men 23 times and women five times more likely to be underweight. Each person normally has a copy of each chromosome from each parent, so we have two copies of each gene. But sometimes...


Word of the Day
lunula
  • A small crescent-shaped structure or marking, especially the white area at the base of a fingernail that resembles a half-moon.
This word is a diminutive of the Latin 'luna,' moon.
Related