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Latest Gene expression profiling in cancer Stories

2013-04-30 10:23:08

-Determining a breast-cancer patient´s prognosis can be difficult because breast tumors contain many genetic differences and there are many subtypes; -This study combined and analyzed large masses of data from 466 cases of the most common type of breast cancer; -The study identified a small group of molecules that might predict breast-cancer prognosis across many subtypes of the disease and at its early stages; -For the first time a prognostic signature in cancer is composed of both...

2013-02-25 10:15:48

Head and neck squamous cell carcinoma (HNSCC) is the seventh most common form of cancer in the United States, but other than an association with the human papillomavirus, no validated molecular profile of the disease has been established. By analyzing data from DNA microarrays, a UNC-led team has completed a study that confirms the presence of four molecular classes of the disease and extends previous results by suggesting that there may be an underlying connection between the molecular...

Biological Diversity In Triple-negative Breast Cancer Discovered By Researchers
2013-02-14 12:25:02

University of North Carolina Health Care Triple-negative breast cancers are more biologically diverse than previously believed and classification should be expanded to reflect this heterogeneity, according to University of North Carolina researchers. In a study published in the February issue of The Oncologist conducted by UNC and the Vall d'Hebron Institute of Oncology in Barcelona, Spain, a team lead by Charles Perou, PhD, of UNC Lineberger Comprehensive Cancer Center, examined more...

2013-01-28 15:46:24

The spread of breast cancer to distant organs within the body, an event that often leads to death, appears in many cases to involve the loss of a key protein, according to UC San Francisco researchers, whose new discoveries point to possible targets for therapy. In the January 27, 2013 online edition of Nature Cell Biology, UCSF scientists describe for the first time how the protein, known as GATA3 – which is abnormal or absent in many cases of human breast cancer – normally...

2012-09-24 13:59:47

A team of scientists with The Cancer Genome Atlas program reports their genetic characterization of 800 breast tumors, including finding some of the genetic causes of the most common forms of breast cancer, providing clues for new therapeutic targets, and identifying a molecular similarity between one sub-type of breast cancer and ovarian cancer. Their findings, which offer a more comprehensive understanding of the mechanisms behind each sub-type of breast cancer, are reported in the...


Word of the Day
call-note
  • The call or cry of a bird or other animal to its mate or its young.
'Call-note' is newer than 'bird-call,' which originally referred to 'an instrument for imitating the note of birds' but now also refers to 'the song or cry of a bird.'
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