Latest Gene expression profiling Stories
There's more than one way to silence gene activity, according to a Michigan State University researcher.Downregulating activity is how healthy genes should shift out of their development cycle. The results, published in this week's Current Biology, discuss how specific repressor proteins "“ which researchers have named Hairy and Knirps "“ slow genes during development and how the process is comparable to slowing down a car, says molecular biologist David Arnosti.The binding of repressor...
REDWOOD CITY, Calif., Feb. 3, 2011 /PRNewswire/ -- Genomic Health, Inc. (Nasdaq: GHDX) today announced that its scientists successfully surveyed expression of the whole human transcriptome using next-generation DNA sequencing technology developed by Illumina, Inc., to test hypotheses for biomarker discovery in archived tumor and normal breast tissue samples. The study identified hundreds of coding and non-coding transcripts that are differentially expressed in tumor versus normal,...
FREMONT, Calif., Jan. 19, 2011 /PRNewswire/ -- WaferGen Biosystems, Inc. (OTC Bulletin Board: WGBS), a leading developer of state-of-the-art genomic analysis systems, today announced that it has appointed world-renowned clinical genomics cancer researcher Arul M. Chinnaiyan, M.D., Ph.D., to its Scientific Advisory Board. Dr. Chinnaiyan is a recognized leader in the use of biomarkers in the clinic to choose appropriate therapies for cancer patients. Biomarkers are characteristics that are...
Research published in the journal GENETICS suggests that being around the opposite sex activates genes in Drosophila melanogaster that cause them to perform certain courtship behaviorsScientists from Texas have made an important step toward understanding human mating behavior by showing that certain genes become activated in fruit flies when they interact with the opposite sex. This research, published in the January 2011 issue of the journal GENETICS (http://www.genetics.org), shows that...
Biologists at Texas A&M University have made an important step toward understanding human mating behavior by showing that certain genes become activated in fruit flies when they interact with the opposite sex.Their research, published in the January 2011 issue of the journal GENETICS, shows that courtship behaviors may be far more influenced by genetics than previously thought. In addition, this new understanding as to why and how these genes become activated within social contexts may...
University of Leicester-led research uncovers potential new approaches for tackling devastating disorderHope for new ways of treating devastating neurodegenerative disorders such as Huntington's disease has been raised by a trans-Atlantic team of researchers thanks to the use of cutting-edge genetic techniques.Led by the University of Leicester, scientists from the University of Lisbon (led by Dr Tiago Outeiro) and University of California at San Francisco (led by Dr Paul Muchowski)...
FREMONT, Calif., Jan. 10, 2011 /PRNewswire/ -- WaferGen Biosystems, Inc. (OTC Bulletin Board: WGBS), a leading developer of state-of-the-art genomic analysis systems, today announced general availability of its Quick-Turnaround SmartChip Custom Panels to enable validation studies of specific genes of interest through customization of high-throughput, real-time PCR SmartChip assay panels -- all on a Quick-Turnaround basis. Using the SmartChip Custom Panels, WaferGen can now offer researchers...
The silencing of specific genes of the germinal cell lines reduces brain tumors in fliesScientists at IRB Barcelona have discovered that some brain tumours in larvae of the fruit fly Drosophila melanogaster use the genetic programme of germline cells to grow. The removal of some of these genes leads to healthy brains. This finding demonstrates that these genes are crucial for tumour development. The study, headed by ICREA researcher Cayetano González, is published today in the prestigious...
IRVINE, California, and AMSTERDAM, December 22, 2010 /PRNewswire/ -- - This release was originally scheduled for distribution on December 20, 2010, 17.00 CET. Due to technical issues it was not distributed Agendia, a world leader in molecular cancer diagnostics, announced today that together with several groups of scientific collaborators it has identified a major role for TSPYL5, one of its MammaPrint breast cancer prognosis genes, in the genesis of breast cancer. The study...
In an examination of leukemic stem cells (LSC), researchers have found that patients with acute myeloid leukemia who had higher activity of certain LSC genes had worse overall, event-free and relapse-free survival, according to a study in the December 22/29 issue of JAMA."In many cancers, specific subpopulations of cells appear to be uniquely capable of initiating and maintaining tumors. The strongest support for this cancer stem cell model comes from transplantation assays in...
