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Last updated on April 19, 2014 at 7:50 EDT

Latest gene expression Stories

2014-04-18 14:05:01

Scientists studying the most common form of inherited mental disability—a genetic disease called “Fragile X syndrome”—have uncovered new details about the cellular processes responsible for the condition that could lead to the development of therapies to restore some of the capabilities lost in affected individuals. In a paper that will be published in the May 8 Molecular Cell, but is being made available this week in the early online edition of the journal, the researchers show...

2014-04-17 15:36:22

A novel application of RNAScope in situ hybridization facilitates gene expression studies in plants Gene expression is the process whereby the genetic information of DNA is used to manufacture functional products, such as proteins, which have numerous different functions in living organisms. Messenger RNA (mRNA) serves as an important intermediary during gene expression, by relating the genetic information of DNA to the molecular mechanisms involved in manufacturing proteins. By...

2014-04-11 10:21:24

ZMYND11 'reads' methylated variant to thwart cancer; tied to breast cancer patient survival A tumor-suppressing protein acts as a dimmer switch to dial down gene expression. It does this by reading a chemical message attached to another protein that's tightly intertwined with DNA, a team led by scientists at The University of Texas MD Anderson Cancer Center reported at the AACR Annual Meeting 2014. The findings, also published in the journal Nature on April 10, provide evidence in...

2014-04-10 16:17:27

Stowers team develops novel assay to identify genes controlling pharynx regeneration in flatworms As multicellular creatures go, planaria worms are hardly glamorous. To say they appear rudimentary is more like it. These tiny aquatic flatworms that troll ponds and standing water resemble brown tubes equipped with just the basics: a pair of beady light-sensing "eyespots" on their head and a feeding tube called the pharynx (which doubles as the excretory tract) that protrudes from a belly sac...

2014-04-09 11:41:42

Results from the study could help determine potential treatment options A quartet of proteins that play critical roles in cell replication, cell death, and DNA repair could lead to better targets for therapy against treatment-resistant head-and-neck squamous cell cancers. In a study to be presented at the AACR Annual Meeting 2014 on Tuesday, April 8, Ranee Mehra, MD, a medical oncologist who specializes in head and neck cancers at Fox Chase Cancer Center, and colleagues, showed a...

2014-04-08 08:30:12

DUBLIN, April 8, 2014 /PRNewswire/ -- Dublin - Research and Markets ( http://www.researchandmarkets.com/research/tf3qn7/cancer_molecular) has announced the addition of the "Cancer Molecular Biomarkers 2014: A Global Market Study" [http://www.researchandmarkets.com/research/tf3qn7/cancer_molecular ] report to their offering. (Logo: http://photos.prnewswire.com/prnh/20130307/600769 ) Technological advances in molecular biology over the last decade are accelerating...

2014-04-07 16:03:04

Some three billion base pairs make up the human genome—the floor plan of life. In 2003, the Human Genome Project announced the successful decryption of this code, a tour de force that continues to supply a stream of insights relevant to human health and disease. Nevertheless, the primary actors in virtually all life processes are the proteins coded for by DNA sequences known as genes. For a broad spectrum of diseases, proteins can yield far more compelling revelations than may be gleaned...

2014-04-07 13:34:30

UC Riverside-led research could help identify new anti-malaria strategies A research team led by a cell biologist at the University of California, Riverside has generated a 3D model of the human malaria parasite genome at three different stages in the parasite's life cycle — the first time such 3D architecture has been generated during the progression of the life cycle of a parasite. The parasite that causes malaria in humans is Plasmodium falciparum. The female Anopheles mosquito...

2014-04-04 11:48:17

Not so long ago researchers thought that RNAs came in two types: coding RNAs that make proteins and non-coding RNAs that have structural roles. Then came the discovery of small RNAs that opened up whole new areas of research. Now researchers have come full circle and predicted that some long non-coding RNAs can give rise to small proteins that have biological functions. A recent study in The EMBO Journal describes how researchers have used ribosome profiling to identify several hundred long...

2014-04-01 13:20:46

Non-coding DNA sequences found in all plants may have undiscovered roles in basic plant development and response to the environment DNA is the molecule that encodes the genetic instructions enabling a cell to produce the thousands of proteins it typically needs. The linear sequence of the A, T, C, and G bases in what is called coding DNA determines the particular protein that a short segment of DNA, known as a gene, will encode. But in many organisms, there is much more DNA in a cell than...