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Latest Genes Stories

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2011-06-15 09:15:00

According to a new study published in the journal Cell, Wnt signaling, already known to control many biological processes, between hair follicles and melanocyte stem cells can determine hair pigmentation. The research at NYU Langone Medical Center was led by Mayumi Ito, PhD, assistant professor at the Ronald O. Pereleman Department of Dermatology at NYU. "We have known for decades that hair follicle stem cells and pigment-producing melanocyte cells collaborate to produce colored hair, but...

2011-06-07 10:15:42

The protein MeCP2 is porridge to the finicky neuron. Like Goldilocks, the neuron or brain cell needs the protein in just the right amount. Girls born with dysfunctional MeCP2 (methyl-CpG-binding protein 2) develop Rett syndrome, a neurological disorder. Too much MeCP2 can cause spasticity or developmental delay with autism-like symptoms in boys. Now, researchers at Baylor College of Medicine and Texas Children's Hospital have found that the neuron needs a steady supply of this protein for its...

2011-05-27 13:37:04

How females select their sexual partners is a matter of more than passing concern to a large number of males.  Focus has gradually switched from the idea that certain males are the most attractive or the best and researchers are increasingly considering the idea that particular individuals might be intrinsically compatible.  Dating agencies routinely include questions about potential partners' hobbies and interests.  Such issues are clearly important but the latest results from...

2011-05-23 21:59:37

Researchers from Mount Sinai School of Medicine have discovered a protein signaling pathway that becomes hyperactivated in human sarcoma cells, suggesting that medications to inhibit this pathway may be effective in the treatment of human sarcomas. The research is published in the current issue of the journal Cancer Cell. A team of researchers led by Stuart Aaronson, MD, Jack and Jane B. Aron Professor and Chairman of the Department of Oncological Sciences at Mount Sinai School of Medicine,...

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2011-05-20 12:45:19

Researchers at the Department of Energy's Oak Ridge National Laboratory and the University of Tennessee have for the first time successfully characterized the earliest structural formation of the disease type of the protein that causes Huntington's disease. The incurable, hereditary neurological disorder is always fatal and affects one in 10,000 Americans.Huntington's disease is caused by a renegade protein "huntingtin" that destroys neurons in areas of the brain concerned with the emotions,...

2011-05-16 19:37:30

Over-activation of a single gene promotes leukemia, but its loss causes liver cancer An international team of researchers, led by scientists at the University of California, San Diego School of Medicine, and the Eastern Hepatobiliary Surgery Hospital in China, say a human gene implicated in the development of leukemia also acts to prevent cancer of the liver. Writing in the May 17 issue of the journal Cancer Cell, Gen-Sheng Feng, PhD, UCSD professor of pathology, and colleagues in San Diego,...

2011-05-16 19:24:39

Worm with abundant ability to regenerate relies on ancient gene to make decisions Most people don't think worms are cool. But the tiny flatworm that Northwestern University scientist Christian Petersen studies can do something very cool indeed: it can regenerate itself from nearly every imaginable injury, including decapitation. When cut in half, it becomes two worms. This amazing ability of the planarian flatworm to regenerate its entire body from a small wedge of tissue has fascinated...

2011-05-12 22:18:51

A seldom-studied gene known as notum plays a key role in the planarian's regeneration decision-making process, according to Whitehead Institute scientists. Protein from this gene determines whether a head or tail will regrow at appropriate amputation sites. Since the late 1800s, scientists have been fascinated by the planarian's amazing ability to regenerate its entire body from a small wedge of tissue. Whitehead Member Peter Reddien and former postdoctoral fellow Christian Petersen recently...

2011-04-20 21:35:00

Rice, Texas A&M labs create protein-patterned fibers Researchers at Rice University and Texas A&M have discovered a way to pattern active proteins into bio-friendly fibers. The "eureka" moment came about because somebody forgot to clean up the lab one night. The new work from the Rice lab of biochemist Kathleen Matthews, in collaboration with former Rice faculty fellow and current Texas A&M assistant professor Sarah Bondos, simplifies the process of making materials with fully...

2011-04-13 21:05:19

NYU School of Medicine researchers find molecules block a crucial cell pathway Researchers from the Cancer Institute at NYU Langone Medical Center have identified three novel small molecules that interrupt a crucial cellular communication pathway that regulates many aspects of development and cancer. The finding, published in the April 12, 2011 issue of the Proceedings of the National Academy of Sciences and featured on its cover, could provide the basis for innovative therapies for...


Latest Genes Reference Libraries

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2011-01-24 12:59:16

The Herpesviridae, a large family of DNA viruses, causes disease in animals and humans. Members of this family are known as herpesviruses. They all share a common structure where they are composed of relatively large double-stranded, linear DNA genomes encoding 100-200 genes encased within an icosahedral protein cage called the capsid. The whole particle is known as a virion. They are all nuclear-replicating. When a viral particle contacts a cell with specific types of receptor molecules...

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