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Latest Genes Stories

2012-11-09 08:27:21

PLYMOUTH, Mich., Nov. 9, 2012 /PRNewswire-USNewswire/ -- ProNAi Therapeutics, Inc., a private DNAi cancer drug development company, recently concluded its initial human clinical trial of PNT2258, a first-in-class, nucleic acid drug. It is presenting the results of the Phase I study of PNT2258, an anti-Bcl-2 cancer drug, at the annual EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, a conference hosted by the European Organization for Research and Treatment of Cancer,...

2012-09-20 23:00:02

Two Mount Sinai School of Medicine researchers are among a select group of scientists from around the world who have been recognized by the National Cancer Institute (NCI) for their quest to answer the most pressing questions about cancer. New York, NY (PRWEB) September 20, 2012 Two Mount Sinai School of Medicine researchers are among a select group of scientists from around the world who have been recognized by the National Cancer Institute (NCI) for their quest to answer the most pressing...

2012-09-20 16:50:12

Scientists have identified a key molecular player in a chain of events in the body that can lead to fatty liver disease, Type II diabetes and other metabolic abnormalities associated with obesity. By blocking this molecule, the researchers were able to reverse some of the pathology it caused in obese mice. Their findings appear in the Proceedings of the National Academy of Sciences. MiR-34a (pronounced MEER-34a), a micro-RNA, occurs at higher than normal levels in the livers of obese...

2012-09-17 23:11:46

A new light-based technique for measuring levels of the toxic protein that causes Huntington's disease (HD) has been used to demonstrate that the protein builds up gradually in blood cells. Published today (17th) in the Journal of Clinical Investigation, the findings shed light on how the protein causes damage in the brain, and could be useful for monitoring the progression of HD, or testing new drugs aimed at suppressing production of the harmful protein. HD is a fatal, incurable, genetic...

2012-09-12 10:26:10

NEW YORK, Sept. 12, 2012 /PRNewswire/ -- BRCA1/2 gene mutations, widely associated with breast and ovarian cancer risks in women, are, in principle, lethal to human embryos, according to new research conducted by three teams of researchers from the Center for Human Reproduction (CHR) in New York City, the Medical University Vienna in Vienna, Austria, and the Medical University Graz, Graz, Austria. BRCA1/2-positive embryos will only survive when also carrying a specific FMR1 gene genotype. In...

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2012-09-06 17:18:38

Brett Smith for redOrbit.com — Your Universe Online The latest IUCN Red List registers Magellanic penguins as ℠Near Vulnerable´ from a conservation standpoint, however a group of scientists from Bowling Green State University want to see if concerns might be tempered or fueled by understanding the genetic diversity amongst the birds´ populations in South America. To measure the amount of genetic diversity in the birds, the researchers focused on the Major...

2012-08-10 02:44:26

High levels of iron could raise the risk of bowel cancer by switching on a key pathway in people with faults in a critical anti-cancer gene, according to a study published in Cell Reports today (Thursday). Cancer Research UK scientists, based at the University of Birmingham and the Beatson Institute for Cancer Research in Glasgow, found bowel cancers were two to three times more likely to develop in mice with a faulty APC gene that were fed high amounts of iron compared to mice who still...

2012-07-17 12:20:03

- Partnership Based on Open Innovation That Leverages Eisai's Natural Product Chemistry-Based Drug Discovery Platform -Tokyo, July 17, 2012 - (JCN Newswire) - Eisai Co., Ltd. announced today that its U.S. subsidiary Eisai Inc. has entered into a research collaboration with U.S. biopharmaceutical company Verastem, Inc. for the generation of small molecule Wnt inhibitors that target cancer stem cells. Based on this agreement, Eisai will synthesize analogs of VS-507 (salinomycin) with the aim of...

Clearer Way To Treat Huntington's Disease Offered By 2 Proteins
2012-07-11 20:58:47

Pair helps remove and prevent misfolding of proteins that cause neurodegeneration In a paper published in the July 11 online issue of Science Translational Medicine, researchers at the University of California, San Diego School of Medicine have identified two key regulatory proteins critical to clearing away misfolded proteins that accumulate and cause the progressive, deadly neurodegeneration of Huntington's disease (HD). The findings explain a fundamental aspect of how HD wreaks havoc...

Why Do Fat Cells Get Fat?
2012-06-25 13:47:23

Surprising finding about WNT signaling points to Sfrp5 as a potential target for anti-obesity drugs As the world fights obesity at the human level, scientists at the University of Michigan and their colleagues have made a surprising finding at the microscopic level that could help fuel that fight. Their work helps explain why fat-storing cells get fatter, and burn fat slower, as obesity sets in. If their findings from mice can be shown to apply to humans, they may provide a new target...


Latest Genes Reference Libraries

69_e588e01b31a2e4f3646b095787aff303
2011-01-24 12:59:16

The Herpesviridae, a large family of DNA viruses, causes disease in animals and humans. Members of this family are known as herpesviruses. They all share a common structure where they are composed of relatively large double-stranded, linear DNA genomes encoding 100-200 genes encased within an icosahedral protein cage called the capsid. The whole particle is known as a virion. They are all nuclear-replicating. When a viral particle contacts a cell with specific types of receptor molecules...

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