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Latest Genetically modified organisms Stories

2009-10-19 07:00:00

ST. LOUIS, Oct. 19 /PRNewswire-FirstCall/ -- Sigma-Aldrich® (Nasdaq: SIAL) today announced the launch of SAGEspeed(TM), a program to develop human disease models in rodents using its proprietary novel CompoZr(TM) Zinc Finger Nuclease (ZFN) gene editing technology (http://www.compozrzfn.com). This program will provide researchers access to custom creation services for developing genetically-engineered 'knockout' rodent animal models for use in research and the...

2009-08-21 08:00:00

ST. LOUIS, Aug. 21 /PRNewswire-FirstCall/ -- Sigma-Aldrich(R) (Nasdaq: SIAL) announced today that scientists at its new Sigma Advanced Genetic Engineering (SAGE(TM)) Labs in St. Louis will leverage its exclusive CompoZr(TM) Zinc Finger Nuclease (ZFN) gene editing technology (www.compozrzfn.com) to define, develop and offer a new generation of genetically-engineered rodent research models. Such models are commonly used to study disease states in humans and play a key role in the drug...

2009-08-13 10:57:15

Investigators at Burnham Institute for Medical Research (Burnham) and the University of Connecticut Health Center (U.C.H.C.) have gained new understanding of the role hyaluronic acid (HA) plays in skeletal growth, chondrocyte maturation and joint formation in developing limbs. Significantly, these discoveries were made using a novel mouse model in which the production of HA is blocked in a tissue-specific manner. The Yamaguchi laboratory genetically modified the Has2 gene, which is a critical...

2009-07-23 14:26:44

Scientists from The Medical College of Wisconsin in Milwaukee, Sangamo Biosciences, Inc., (NASDAQ: SGMO), Sigma-Aldrich Corporation (NASDAQ: SIAL), Open Monoclonal Technology, Inc. (OMT) and INSERM today announced the creation of the first genetically modified mammals developed using zinc finger nuclease (ZFN) technology.In a paper published in the July 24, 2009 issue of Science, researchers describe the novel application of ZFNs to generate rats with permanent, heritable gene mutations,...

2009-07-23 14:21:55

Open Monoclonal Technology, Inc. (OMT), in collaboration with Sangamo BioSciences, Inc. (NASDAQ, SGMO), Sigma-Aldrich Corporation (NASDAQ: SIAL), The Medical College of Wisconsin, and INSERM, today announced the creation of the first targeted knockout rats as detailed in "Knockout Rats Produced via Embryo Microinjection of Designed Zinc Finger Nucleases," published in the July 24th issue of Science. The creation of rats with permanent, heritable genetic mutations is a critical milestone in...

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2009-07-01 10:55:00

Deleting two genes in mice responsible for repairing DNA strands damaged by oxidation leads to several types of tumors, providing additional evidence that such stress contributes to the development of cancer. That's the conclusion of a recent study* in DNA Repair by researchers at the National Institute of Standards and Technology (NIST), Oregon Health and Science University (OHSU) and the New York University School of Medicine (NYUSM).Although all cells need oxygen to survive, the element...

2009-06-24 08:42:16

Scientists of the German Mouse Clinic at Helmholtz Zentrum Mnchen have generated and analyzed a mouse model in which parts of the human Foxp2 gene were introduced. Foxp2 is known to be a key gene for language. Since the human and chimpanzee lineages diverged, only minimal genetic alterations have occurred, even with reference to the mouse: The alterations, as scientists surmised, are closely associated with speech and language ability. However, proof on a functional level has been lacking...

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2008-01-14 15:55:00

Obesity quick fix unlikely; problem even more complex than previously thoughtPHILADELPHIA "“ Reporting in the online journal BMC Genetics, researchers from the Monell Center have for the first time attempted to count the number of genes that contribute to obesity and body weight. The findings suggest that over 6,000 genes "“ about 25 percent of the genome "“ help determine an individual's body weight. "Reports describing the discovery of a new "Ëœobesity gene' have...

2006-04-03 05:47:10

By Jeremy Smith BRUSSELS (Reuters) - Environmental group Friends of the Earth on Monday accused the European Commission of favoring the biotech industry in its vision of how GMO crops could be grown alongside organic and traditional types. In a report issued on the eve of an EU conference on the subject in Vienna, FoE said the Commission's approach, far from avoiding contamination and protecting health and the environment, was to ensure that GMO trade went unimpeded. The Commission,...


Latest Genetically modified organisms Reference Libraries

GloFish
2013-10-03 10:12:03

The GloFish is a patented and trademarked brand of genetically modified fluorescent fish. Various GloFish are currently on the market. Zebrafish were the first GloFish that were available within pet stores and are now sold in bright green, red, orange-yellow, blue, and purple fluorescent colors. Recently, Electric Green, Sunburst Orange, and Moonrise Pink colored tetra (Gymnocorymbus ternetzi) and Electric Green tiger barb (Puntius tetrazona) have been incorporated to the lineup. Although not...

Knockout Mouse
2013-10-02 11:52:01

A Knockout Mouse is a genetically engineered mouse in which researchers have inactivated, or “knocked out,” an existing gene by replacing it or disrupting it with an artificial piece of DNA. The loss of gene activity frequently causes changes in a mouse’s phenotype, which includes appearance, behavior, or other apparent and biochemical characteristics. Knockout mice are significant animal models for studying the role of genes which have been sequenced but whose functions haven’t...

Herman The Bull
2013-10-02 08:47:12

Herman the Bull was the first genetically modified or transgenic bovine in the world. The publication of Herman’s creation caused an ethical storm. At the early embryo stage, Herman was genetically engineered within a laboratory by Gen Pharm International of Mountain View, California. Scientists microinjected cells with the human gene coding for lactoferrin. The Dutch Parliament changed law in December of 1992 to enable Herman to reproduce. Eight calves were born in 1994 following a...

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Word of the Day
toccata
  • In music, a work for a keyboard-instrument, like the pianoforte or organ, originally intended to utilize and display varieties of touch: but the term has been extended so as to include many irregular works, similar to the prelude, the fantasia, and the improvisation.
This word is Italian in origin, coming from the feminine past participle of 'toccare,' to touch.
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