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Latest Genome-wide association study Stories

2014-08-04 12:44:15

Dana-Farber Cancer Institute Discovery could lead to future screening tests A large DNA analysis of people with and without pancreatic cancer has identified several new genetic markers that signal increased risk of developing the highly lethal disease, report scientists from Dana-Farber Cancer Institute. The markers are variations in the inherited DNA code at particular locations along chromosomes. Several of these variations in the DNA code were identified that influence an...

2014-07-22 00:21:12

Genes, pathways identified could inform new approaches to treatment CAMBRIDGE, Mass., July 21, 2014 /PRNewswire/ -- As part of a multinational, collaborative effort, researchers from the Broad Institute, Massachusetts General Hospital (MGH), and scores of other institutions from all over the world have helped identify over 100 locations in the human genome associated with the risk of developing schizophrenia in what is the largest genomic study published on any psychiatric disorder...

2014-06-30 12:32:32

--CHOP Study: Patients with Specific Gene Variants May Require Higher Doses of Pain-Control Drugs-- PHILADELPHIA, June 30, 2014 /PRNewswire-USNewswire/ -- In the first genome-wide analysis of postsurgical pain in children, pediatric researchers identified variations in genes that affect a child's need for pain-control drugs. The findings suggest that at some point physicians may calibrate pain-medication dosages according to a child's individual genetic makeup....

2014-05-30 11:24:36

Georgia Institute of Technology A study of 338 patients with coronary artery disease has identified a gene expression profile associated with an elevated risk of cardiovascular death. Used with other indicators such as biochemical markers and family history, the profile – based on a simple blood test – may help identify patients who could benefit from personalized treatment and counseling designed to address risk factors. Researchers found the risk signature by comparing gene...

2014-05-08 09:51:38

Old data can be mined to find new genetic associations and gene interactions The power of genome-wide association studies (GWAS) to detect genetic influences on human disease can be substantially increased using a statistical testing framework reported in the May issue of the journal GENETICS. Despite the proliferation of GWAS, the associations found so far have largely failed to account for the known effects of genes on complex disease — the problem of "missing heritability."...

Largest Study Yet Of Diabetes Genetics Brings In Data From Different Ethnic Groups
2014-02-10 10:49:21

University of Oxford Seven new genetic regions associated with type 2 diabetes have been identified in the largest study to date of the genetic basis of the disease. DNA data was brought together from more than 48,000 patients and 139,000 healthy controls from four different ethnic groups. The research was conducted by an international consortium of investigators from 20 countries on four continents, co-led by investigators from Oxford University's Wellcome Trust Centre for Human...

New Genetic Associations For Asthma-With-Hay Fever Identified
2014-01-29 14:09:31

23andMe First Ever Genome-Wide Association Study of Combined Phenotype May Allow for Improved Identification of Variants Associated with Asthma-With-Hay Fever 23andMe, the leading personal genetics company, has participated in the first ever genome-wide association study of the combined asthma-with-hay fever phenotype.  Led by researchers at the QIMR Berghofer Medical Research Institute, the study identified 11 independent genetic markers associated with the development of...

2013-08-06 09:13:17

A study by Valentina Moskvina, Ph.D., of the Cardiff University School of Medicine, Wales, United Kingdom, and colleagues, examined the genetic overlap between Parkinson disease (PD) and Alzheimer disease (AD). Data sets from the United Kingdom, Germany, France and the United States were used to perform a combined genome-wide association analysis (GWA). The GWA study of AD included 3,177 patients with AD and 7,277 control patients, and the GWA analysis for PD included 5,333 patients with...

Scientists Hope To Improve Genome-wide Association Studies With Two New Methods
2013-04-26 11:25:54

University of California - San Diego As scientists probe and parse the genetic bases of what makes a human a human (or one human different from another), and vigorously push for greater use of whole genome sequencing, they find themselves increasingly threatened by the unthinkable: Too much data to make full sense of. In a pair of papers published in the April 25, 2013 issue of PLOS Genetics, two diverse teams of scientists, both headed by researchers at the University of California,...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.