Latest Genome-wide association study Stories

2009-09-23 09:11:43

Walter and Eliza Hall Institute researchers are part of an international team that has discovered a genetic variation that could identify those people infected with hepatitis C who are most likely to benefit from current treatments. Dr Melanie Bahlo and Dr Max Moldovan from the institute's Bioinformatics division worked with researchers from the University of Sydney and elsewhere to analyze the genomes of more than 800 people, including more than 300 Australians, who were receiving treatment...

2009-07-17 09:00:19

Findings may point to new avenues for treatment, prevention A team led by researchers from the National Institutes of Health today reported the discovery of five genetic variants related to blood pressure in African-Americans, findings that may provide new clues to treating and preventing hypertension. The effort marks the first time that a relatively new research approach, called a genome-wide association study, has focused on blood pressure and hypertension in an African-American...

2009-07-15 11:37:06

Important questions raised about genetic research based only on blood samples; new treatment in vascular disease foreseen at the same timeResearch by a group of Montreal scientists calls into question one of the most basic assumptions of human genetics: that when it comes to DNA, every cell in the body is essentially identical to every other cell. Their results appear in the July issue of the journal Human Mutation.This discovery may undercut the rationale behind numerous large-scale genetic...

2009-06-30 15:51:56

An analysis of the association between genetic variations of the inflammation biomarker C-reactive protein (CRP) with coronary heart disease failed to support a causal association, according to a study in the July 1 issue of JAMA.Coronary heart disease (CHD) is the leading cause of death worldwide. Inflammation plays a key role in the development of CHD at every stage, from initiation to progression and rupture of plaque. CRP is currently the most widely used biomarker of inflammation,...

2009-06-30 15:42:27

A protein used by doctors to indicate a patient's risk of coronary heart disease may have drug developers barking up the wrong treatment tree, according to the authors of a study published today in the Journal of the American Medical Association (JAMA). Their research suggests that C-reactive protein, an enticing target for scientists working on new treatments for coronary heart disease, may not have a role in causing the disease, even though it is a predictive marker.Coronary heart disease...

2009-05-25 09:39:29

For the first time, scientists have been able to identify genetic factors that influence the age at which natural menopause occurs in women. Ms Lisette Stolk, a researcher from Erasmus MC, Rotterdam, The Netherlands, told the annual conference of the European Society of Human Genetics today ( Monday 25 May) that a greater understanding of the factors influencing age at menopause might eventually help to improve the clinical treatment of infertile women. Ms Stolk and her team performed a...

2009-05-11 07:10:49

An international research team has identified a number of unsuspected genetic variants associated with systolic blood pressure (SBP), diastolic blood pressure (DBP), and hypertension (high blood pressure), suggesting potential avenues of investigation for the prevention or treatment of hypertension. The research was funded in part by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health and by several other NIH institutes and centers. The analysis of over...

2009-05-11 07:05:53

8 DNA regions associated with blood pressure and hypertension, 6 for first time Scientists from Massachusetts General Hospital (MGH), as part of a major international research collaboration, have associated common variants in eight regions of DNA with blood pressure levels in human patients. Six of the identified regions have not previously been implicated in blood pressure regulation. In their study, receiving advance online publication in Nature Genetics, members of the Global Blood...

2009-02-26 11:00:00

- Broadens Power of Current Genetic Discovery Techniques - PHILADELPHIA, Feb. 26 /PRNewswire-USNewswire/ -- Discovering the different genes that contribute to a complex disease is like searching in the proverbial haystack for an unknown number of needles -- some much smaller than others, often blending into the background, and many of them widely separated from each other. But if some needles are linked to each other by fine threads, you might pull out clumps of them together. Using a novel...

2009-02-26 11:59:22

AssociationViewer will explore links between genes and disease Modern genotyping technologies offer new opportunities to explore how genes influence health and disease, but also present the challenge of analyzing huge amounts of genetic and clinical data. With this in mind, investigators at the Lausanne Branch of the international Ludwig Institute for Cancer Research (LICR), the Swiss Institute of Bioinformatics (SIB) and the University Hospital of Lausanne have developed AssociationViewer, a...

Word of the Day
  • Remarkable; prodigious.
  • Audacious; gutsy.
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  • Audaciously; boldly.
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This word is probably from the dialectal 'boldacious,' a blend of 'bold' and 'audacious.'