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Latest Genomes Project Stories

2012-02-17 00:31:25

Researchers develop a new catalogue to help identify gene variations associated with disease A high-quality reference catalogue of the genetic changes that result in the deactivation of human genes has been developed by a team of researchers. This catalogue of loss-of-function (LoF) variants is needed to find new disease-causing mutations and will help us to better understand the normal function of human genes. In addition, the researchers report that each of us is carrying around 20 genes...

2011-08-25 14:53:06

New gene identified that affects levels of pain in osteoarthritis following use of 1000 Genomes study data Researchers have today revealed a new gene associated with osteoarthritis. This is only the third gene to be identified for this painful and debilitating disease that affects more than 40 per cent of people aged more than 70 years. The disease-associated variant, in the gene MCF2L, was discovered when Wellcome Trust Sanger Institute researchers used data from the 1000 Genomes...

2011-07-25 15:49:32

The study on single-nucleotide resolution structural variations (SVs) of an Asian and African genome was published online in Nature Biotechnology. This study was performed by BGI (previously known as the Beijing Genomics Institute), the largest genomics organization in the world, and demonstrates that whole genome de novo assembly could serve as a new solution for developing a more comprehensive SV map of individuals. With the rapid development of genomics, more and more experts focus upon...

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2011-06-13 05:30:00

Researchers have discovered that parents give their children about 60 new genome mutations. The new value is reported in the first-ever direct study of new mutations coming from mother and father. Researchers measured directly the number of mutations in two families, using whole genome sequences from the 1000 Genomes Project.  The results also reveal that human genomes, like all genomes, are changed by the forces of mutation. New mutations are the ultimate source from which new...

2011-02-17 21:30:38

Dominant model of human adaptation may have played smaller role than thought The most popular model used by geneticists for the last 35 years to detect the footprints of human evolution may overlook more common subtle changes, a new international study finds. Classic selective sweeps, when a beneficial genetic mutation quickly spreads through the human population, are thought to have been the primary driver of human evolution. But a new computational analysis, published in the February 18,...

2011-02-03 13:11:24

Boston College bioinformatics lab's analysis supports 1000 Genomes Project Analyzing billions of pieces of genetic data collected from people around the world, Boston College biologist Gabor Marth and his research team are playing an integral role in the global effort to sequence 1000 genomes and move closer to understanding in fine detail how genetics influence human health and development. The most comprehensive map to date of genomic structural variants "“ the layer of our DNA that...

2011-02-02 19:41:40

Comprehensive catalogue uncovers genetic sequence of large-scale differences between human genomes A detailed analysis of data from 185 human genomes sequenced in the course of the 1000 Genomes Project, by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, in collaboration with researchers at the Wellcome Trust Sanger Institute in Cambridge, UK, as well as the University of Washington and Harvard Medical School, both in the USA, has identified the genetic...

2011-02-02 19:40:17

A study from the 1000 Genomes Project yields data for analyzing structural variants in DNA Advances in DNA sequencing technology have revolutionized biomedical research and taken us another step forward in personalized medicine. Now, scientists led by Brigham and Women's Hospital (BWH), Harvard Medical School (HMS), the Broad Institute, the Wellcome Trust Sanger Institute (WTSI), the University of Washington, and the European Molecular Biology Laboratory, have developed a new framework for...


Word of the Day
jument
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.
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