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Latest genotype Stories

Australia Suffers Under New Strain Of Whooping Cough
2012-03-22 05:50:54

A new strain of whooping cough has been eluding vaccines and causing the number of whooping cough cases to rise sharply in Australia. Scientists from the University of New South Wales led the research and discovered a new genotype (called prn2-ptxP3) of B. pertussis, the whooping cough bacteria. This new strain has been resistant to the current acellular vaccine (ACV) given to treat whooping cough. As such, cases of the potentially fatal respiratory illness are on the rise. These...

2012-03-07 11:00:53

Two studies published March 6 in the Journal of the National Cancer Institute provide insights about the CYP2D6 genotype in postmenopausal breast cancer patients and represent a major step forward in understanding the usefulness of CYP2D6 testing for deciding whether or not a patient should receive adjuvant tamoxifen for treatment of early-stage breast cancer. Both studies found that CYP2D6 genotypes that were indicative of reduced activity of enzymes that metabolize tamoxifen did not predict...

2012-02-21 11:40:16

A towering $60,000 bill, a year of fierce, flu-like symptoms and a running risk of depression are among the possible costs of two new hepatitis C treatments. But according to Stanford University health policy researchers, they might be worth it. Using a computer model of hepatitis C disease – which accounts for different treatments, outcomes, disease stages and genetics – a research team led by Jeremy Goldhaber-Fiebert, PhD, found that new triple-therapies for genotype-1...

2012-01-19 11:31:56

Researchers targeted the type of hepatitis C most common in the United States, results reported in New England Journal of Medicine A new combination of investigational drugs successfully suppressed hepatitis C genotype 1 infection in a high percent of patients who had not responded to previous treatment in a study led by a University of Michigan hepatologist. The study, which will be published Jan. 19 in the New England Journal of Medicine, focused on hepatitis C genotype 1, which is...

2011-12-28 07:54:24

Although the U.S. Food and Drug Administration (FDA) has recommended that a certain type of genetic testing (for the genotype CYP2C19) be considered before prescribing the drug clopidogrel to identify individuals who may be less responsive to the medication, a review and analysis of previous studies did not find an overall significant association between the CYP2C19 genotype and cardiovascular events, according to a study in the December 28 issue of JAMA. Clopidogrel is an antiplatelet...

2011-12-16 13:59:19

Parkinson's disease is marked by the abnormal accumulation of α-synuclein and the early loss of dopamine neurons in the substantia nigra region of the brain. A polymorphism in the promotor of α-synuclein gene known as NACP-Rep1 has been implicated as a risk factor for the disease. Now, researchers have found that different variants of NACP-Rep1 and its interaction with the microtubule-associated protein tau (MAPT) H1 haplotype can influence the speed of clinical...


Word of the Day
penuche
  • A fudgelike confection of brown sugar, cream or milk, and chopped nuts.
'Penuche' is a variant of 'panocha,' a coarse grade of sugar made in Mexico. 'Panocha' probably comes from the Spanish 'panoja, panocha,' ear of grain.
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