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Latest Glial scar Stories

2014-06-25 10:25:31

Ohio State University Study in mice suggests immune cells fail to activate key messenger needed for repair In the complex environment of a spinal cord injury, researchers have found that immune cells in the central nervous system of elderly mice fail to activate an important signaling pathway, dramatically lowering chances for repair after injury. These studies were the first to show that spinal cord injuries are more severe in elderly mice than in young adults, corroborating...

Technology Developed To Regenerate Functional Neurons
2013-12-19 12:28:31

Penn State Researchers at Penn State University have developed an innovative technology to regenerate functional neurons after brain injury, and also in model systems used for research on Alzheimer's disease. The scientists have used supporting cells of the central nervous system, glial cells, to regenerate healthy, functional neurons, which are critical for transmitting signals in the brain. Gong Chen, a professor of biology, the Verne M. Willaman Chair in Life Sciences at Penn State,...

2012-06-01 09:54:11

A protein produced by the central nervous system´s support cells seems to play two opposing roles in protecting nerve cells from damage, an animal study by Johns Hopkins researchers suggests: Decreasing its activity seems to trigger support cells to gear up their protective powers, but increasing its activity appears to be key to actually use those powers to defend cells from harm. Seth Blackshaw, Ph.D., an associate professor in the Solomon H. Snyder Department of Neuroscience at the...

2012-04-18 09:16:59

Combined, complimentary therapies have the ability to maximize the benefits of neural stem cell (NSC) transplantation for spinal cord repair in rat models, according to a study carried out by a team of Korean researchers who published in a recent issue of Cell Transplantation (20:9), now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/. "When transplanted, neural stem cells have demonstrated their therapeutic potential to reverse complex pathological processes...

2012-03-29 22:24:42

A type of cell plentiful in the brain, long considered mainly the stuff that holds the brain together and oft-overlooked by scientists more interested in flashier cells known as neurons, wields more power in the brain than has been realized, according to new research published today in Science Signaling. Neuroscientists at the University of Rochester Medical Center report that astrocytes are crucial for creating the proper environment for our brains to work. The team found that the cells...

2012-03-15 05:39:01

(Ivanhoe Newswire)– Pill for spinal injury? A new study shows an oral drug that has shown promise in trials for human multiple sclerosis, significantly improves locomotor recovery in mice with spinal cord injury (SCI). Researchers uncover how a new pill that has shown positive results in mice with multiple sclerosis suffering from deterioration of the spinal cord, may help humans. Aside from the initial tissue damage, a great deal of the degradation of the spinal cord in SCI is...

2012-03-13 10:31:19

Results reported in the American Journal of Pathology A new study suggests that administering FTY720, an oral drug that has shown promise in trials for human multiple sclerosis, significantly improves locomotor recovery in mice with spinal cord injury (SCI). The research suggests a possible new avenue to counteract the degeneration of the spinal cord in human SCI. The study will be published in the April 2012 issue of The American Journal of Pathology. Beyond the initial tissue damage,...

2011-12-12 16:05:14

Development: How specific cells are generated in the spinal cord How astrocytes, certain cells of the nervous system, are generated was largely unknown up to now. Bochum's researchers have now investigated what influence the cell environment, known as the extracellular matrix, has on this process. They found out that the matrix protein tenascin C has to be present in order for astrocytes to multiply and distribute in a controlled fashion in the spinal cord of mice. Together with colleagues...

2011-10-28 12:15:05

Italian and Spanish scientists studying the use of stem cells for treating spinal cord injuries have provided the first evidence to show that meninges, the membrane which envelops the central nervous system, is a potential source of self-renewing stem cells. The research, published in STEM CELLS, develops the understanding of cell activation in central nervous system injuries; advancing research into new treatments for spinal injuries and degenerative brain disorders. The team focused...

2011-07-07 20:33:05

Lesions to the brain or spinal cord rarely heal fully, which leads to permanent functional impairment. After injury to the central nervous system (CNS), neurons are lost and largely replaced by a scar often referred to as the glial scar based on its abundance of supporting glial cells. Although this process has been known to science for over a century, the function of the scar tissue has long been disputed. However, there are indications that it stabilizes the tissue and that it inhibits the...


Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
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