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Latest glioblastoma Stories

2009-07-31 08:44:46

Cancer researchers at Georgetown University's Lombardi Comprehensive Cancer Center have successfully tested a small, engineered antibody they say shuts down growth of human glioblastoma tumors in cell and animal studies. Glioblastoma is the deadliest of brain cancers; there is no effective treatment.In the current online issue of the journal Oncogene, the researchers demonstrate how this antibody latches onto a receptor that studs the outside of glioblastoma cells, preventing a growth factor...

2009-07-06 15:11:39

Mayo Clinic and University of California-San Francisco medical researchers say they have found a connection between DNA alterations and brain cancer. The scientists say they found a linkage between DNA variations on human chromosome 9 and aggressive brain cancer known as glioblastoma. The study, conducted with different patient populations at each institution, looked for genome-wide associations. The researchers said they found that people with the specific DNA alterations -- also known as...

2009-06-02 09:27:09

Findings in mice suggest greater hope for targeting brain cancer, but also greater caution in pursuing stem cell treatments for degenerative diseases University of Michigan scientists have found that a deficiency in a key tumor suppressor gene in the brain leads to the most common type of adult brain cancer. The study, conducted in mice that mimic human cancer, points the way to more effective future treatments and a way to screen for the disease early.Appearing June 2 in Cancer Cell, the U-M...

2009-04-04 11:11:32

 Duke University researchers have identified a receptor on the surface of cells that may give them another avenue of attack against glioblastoma, the most common and most deadly type of brain cancer.The neurokinin 1 receptor (NK1R), which may be expressed in all human glioblastoma cells, may prove to be an appropriate target for therapies aimed at treating these brain tumors, according to a study led by researchers in the Duke Department of Anesthesiology and the Preston Robert Tisch...

2009-03-13 14:37:49

A newly identified molecular pathway that directs stem cells to produce glial cells yields insights into the neurobiology of Down's syndrome and a number of central nervous system disorders characterized by too many glial cells, according to a recent study by researchers at the Salk Institute for Biological Studies.Their findings, to be published in the March 13 online edition of Cell Death and Differentiation, indicate that synaptojanin-1, a central component of the pathway, is essential to...

2009-01-14 07:03:06

Glioblastoma, the most common and aggressive type of brain tumor, accounts for a majority of the brain tumors seen in patients 65 years or older. This segment of the population is growing faster than any other age group and not surprisingly, the incidence of glioblastoma in older adults is on the rise. Because survival in older patients tends to be short and they have a higher risk of suffering debilitating side effects from therapy, physicians are unsure how to manage their treatment. A new...

2009-01-05 14:47:09

U.S. researchers using mice have developed a model of the most common and deadly human brain cancer, a published study indicates. The findings advance scientists' understanding of glioblastoma, the most common and most aggressive type of primary brain tumor, accounting for 52 percent of all primary brain-tumor cases, said Inder Verma, professor in the Laboratory of Genetics at the Salk Institute in La Jolla, Calif. The researchers sought to mimic randomly occurring mutations that lie at the...

2009-01-05 09:28:00

Researchers at the Salk Institute for Biological Studies have developed a versatile mouse model of glioblastoma "” the most common and deadly brain cancer in humans "” that closely resembles the development and progression of human brain tumors that arise naturally. "Mouse models of human cancer have taught us a great deal about the basic principles of cancer biology," says Inder Verma, Ph.D., a professor in the Laboratory of Genetics. "By definition, however, they are just that:...

2008-12-29 13:58:55

New discovery could allow for direct delivery of treatments UC Davis Cancer Center researchers report today the discovery of a molecule that targets glioblastoma, a highly deadly form of cancer. The finding, which is published in the January 2009 issue of the European Journal of Nuclear Medicine and Molecular Imaging, provides hope for effectively treating an incurable cancer. Glioblastoma is the most common and aggressive type of primary brain tumor in adults. It is marked by tumors with...

2008-11-12 09:00:10

ImmunoCellular Therapeutics, Ltd. (OTCBB:IMUC)(IMUC), a biotechnology company, presented data showing an immunological response against cancer stem cells (CSCs) derived from brain cancer, specifically glioblastoma. It has been demonstrated in the last few years that CD-133, a cell surface marker, is present on many different types of cancer stem cells and should therefore make an excellent target for ICT-121, the company's cancer stem cell vaccine product candidate, which is specifically...