Latest glioblastoma Stories

By Mercier, Marie Le Mathieu, Veronique; Haibe-Kains, Benjamin; Bontempi, Gianluca; Mijatovic, Tatjana; Decaestecker, Christine; Kiss, Robert; Lefranc, Florence Abstract Galectin (Gal) 1 is a hypoxia-regulated proangiogenic factor that also directly participates in glioblastoma cell migration. To determine how Gal-1 exerts its proangiogenic effects, we investigated Gal-1 signaling in the human Hs683 glioblastoma cell line. Galectin 1 signals through the endoplasmic reticulum transmembrane...

By Yip, Stephen Iafrate, A John; Louis, David N Abstract Advances in understanding the molecular underpinnings of cancer and in molecular diagnostic technologies have changed the clinical practice of oncologic pathology. The development of targeted therapies against specific molecular alterations in cancer further portends changes in the role of the pathology laboratory to guide such custom therapies. To reconcile the flood of scientific discoveries in this area, the promises of highly...