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Latest glioblastomas Stories

2013-06-02 23:15:45

Voices Against Brain Cancer comments on a potential new target that gives promise for treating glioblastomas. New York, NY (PRWEB) June 01, 2013 On June 1, Voices Against Brain Cancer, an organization dedicated to brain cancer research and advocacy, comments on a possible new target that may enhance brain cancer treatment. According to a Futurity.org article, researchers are working on targeting a specific enzyme that may be able to inhibit and kill glioblastoma cells and other forms of...

Genetic Cause Of Most Lethal Brain Tumor Discovered-- Could Lead To New Treatment
2012-07-26 13:46:21

Researchers at Columbia University Medical Center (CUMC) have discovered that some cases of glioblastoma, the most common and aggressive form of primary brain cancer, are caused by the fusion of two adjacent genes. The study also found that drugs that target the protein produced by this genetic aberration can dramatically slow the growth of glioblastomas in mice. The findings were published today in the online edition of the journal Science. "Our findings are doubly important," said study...

2011-12-02 01:49:00

Novel observation may help explain resistance to targeted therapies A small percentage of the deadly brain tumors called glioblastomas, which usually resist treatment with drugs targeting mutations in cell-growth genes, appears to contain extra copies of two or three of these genes at the same time. The surprising discovery by a Massachusetts General Hospital (MGH)-based research team has major implications for the understanding of tumor biology — including the evolution of tumor...

2011-11-14 23:16:11

Glioblastoma multiforme (GBM) is the most common malignant brain cancer in humans. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant to current therapies. A team of researchers -- led by Bo Hu and Shi-Yuan Cheng, at the University of Pittsburgh Cancer Institute, Pittsburgh -- has now identified a molecular pathway that drives the aggressive cancerous nature of a substantial proportion of glioblastomas; specifically, those that...

2011-09-15 20:42:39

A new study suggests that blocking cancer cells' access to cholesterol may offer a new strategy for treating glioblastoma, the most common and deadly form of brain cancer, and perhaps other malignancies. The potential treatment could be appropriate for tumors with a hyperactive PI3K signaling pathway, which accounts for up to 90 percent of glioblastomas cases. Researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove...

2011-01-05 09:04:37

(Ivanhoe Newswire) -- The deletion of a gene called NFKBIA may cause glioblastoma, the most common and malignant brain cancer. Researchers at the Stanford University School of Medicine recently discovered that the deletion of this gene, which is known to promote tumor development and resistance to therapy, was present in one out of every four glioblastoma cases. When NFKBIA is deleted, certain biochemical processes occur with striking similarity to an onset of glioblastoma, which often...

2010-12-23 16:54:43

A study fast-tracked for online publication Dec. 22 in the New England Journal of Medicine has identified an important gene deletion in up to one of every four cases of glioblastoma, the most common adult brain cancer. This deletion contributes to tumor development, promotes resistance to therapy and considerably worsens a patient's survival prospects. The deletion of the gene, known as NFKBIA, triggers biochemical processes similar to those resulting from a better-known aberration common in...

2010-07-23 13:10:19

Patients with deadly glioblastomas who received high doses of radiation that hit a portion of the brain that harbors neural stem cells had double the progression-free survival time as patients who had lower doses or no radiation targeting the area, a study from the Radiation Oncology Department at UCLA's Jonsson Comprehensive Cancer Center has found. Patients who underwent high doses of radiation that hit the specific neural stem cell site, known as the stem cell niche, experienced 15 months...

2010-07-06 13:55:24

In their latest research, scientists of the Max Delbrck Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have demonstrated how the brain's own stem cells and precursor cells control the growth of glioblastomas. Of all brain tumors, glioblastomas are among the most common and most aggressive. Dr. Sridhar Reddy Chirasani, Professor Helmut Kettenmann and Dr. Rainer Glass (all MDC) and Dr. Michael Synowitz (Charit© "“ Universitätsmedizin Berlin) have now shown in cell...

2010-04-18 09:51:21

DNA modification defines early onset glioblastoma, is prevalent in lower grade gliomas HOUSTON - A class of brain tumor that tends to emerge in younger patients but is less aggressive than others can be identified by examining DNA methylation of a specific set of genes, scientists at The University of Texas M. D. Anderson Cancer Center and colleagues with The Cancer Genome Atlas report today online at Cancer Cell. The national research group discovered that hypermethylation is a defining...


Word of the Day
humgruffin
  • A terrible or repulsive person.
Regarding the etymology of 'humgruffin,' the OED says (rather unhelpfully) that it's a 'made-up word.' We might guess that 'hum' comes from 'humbug' or possibly 'hum' meaning 'a disagreeable smell,' while 'gruffin' could be a combination of 'gruff' and 'griffin.'