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Latest Glomerulus Stories

2014-04-11 10:16:28

To accommodate a lifetime of scents and aromas, mammals have hundreds of genes that each produce a different odorant receptor. The complex and diverse olfactory system they build remains adaptable, but a new study in the journal Science shows that the system's flexibility, or plasticity, has its limits. Working in mice, Brown University scientists found that the fundamental neural wiring map between the nose and the brain becomes established in a critical period of early development and then...

2014-04-11 10:13:44

Stowers investigators reveal a developmental switch in targeting capacity of olfactory neurons The human nose expresses nearly 400 odorant receptors, which allow us to distinguish a large number of scents. In mice the number of odor receptors is closer to 1000. Each olfactory neuron displays only a single type of receptor and all neurons with the same receptors are connected to the same spot, a glomerulus, in the brain. This convergence, or wiring pattern, is often described as an...

2014-03-04 15:57:46

Drug Research and Development should target cell-cell interactions that promote disease progression Prevention and reversal of chronic kidney disease is an urgent public health need. The disease affects 1 in 10 Americans, is debilitating and deadly, and existing drugs, at best, offer only mild delay in progression to end-stage kidney failure. New research led by Icahn School of Medicine at Mount Sinai investigators has uncovered abnormal molecular signaling pathways from disease initiation...

How Flies Avoid Rotten Food
2012-12-07 07:23:29

[ Watch the Video: Flies Sniff Out and Avoid Spoiled Food ] April Flowers for redOrbit.com - Your Universe Online Eating spoiled food can be fatal as it allows bacterial pathogens to enter the digestive system. One of the main tasks of the sense of smell is to detect signs of decay, allowing us and other animals to avoid such food poisoning. A new study, conducted by behavioral scientists and neurobiologists at the Max Planck Institute for Chemical Ecology, has decoded the neural...

2011-12-05 13:01:24

Damage to podocytes -- a specialized type of epithelial cell in the kidney -- occurs in more than 90 percent of all chronic kidney disease. Now researchers at the Stanford University School of Medicine have uncovered an unexpected pathway that reveals for the first time how these cells may regenerate and renew themselves during normal kidney function. This finding is an important step toward one day therapeutically coaxing the cells to divide, which could be used to treat people with...

2010-10-18 21:45:25

'Sister' mitral cells may broadcast 2 distinct channels of information on odors to the cortex A team co-led by neuroscientists at Cold Spring Harbor Laboratory (CSHL) has shed light -- literally -- on circuitry underlying the olfactory system in mammals, giving us a new view of how that system may pull off some of its most amazing feats. It has long been known from behavioral experiments that rodents, for instance, can tell the difference between two quite similar odors in a single sniff. But...

2009-02-03 12:46:49

Arrangement of receptors appears uniformly random across individuals and speciesDespite the striking aromatic differences between coffee, peppermint, and pine, a new mapping of the nose's neural circuitry suggests a haphazard patchwork where the receptors for such disparate scents are as likely as not to be neighbors.Inexplicably, this seemingly random arrangement is faithfully preserved across individuals and even species, with cells that process the same scent located in precisely the same...


Word of the Day
ramage
  • Boughs or branches.
  • Warbling of birds in trees.
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