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Latest Glucagon Stories

2011-06-16 01:09:00

COPENHAGEN, Denmark and INGELHEIM, Germany, June 16, 2011 /PRNewswire/ -- - Boehringer Ingelheim Obtains Global Rights to glucagon/GLP-1 Dual Agonists, including ZP2929, Zealand Pharma's Lead Drug Candidate in This Class - Zealand Pharma is Eligible to Receive Total Projected Milestone Payments of up to EUR376 million for ZP2929 Today,...

2011-05-13 10:26:30

HDAC inhibitors may provide a novel way to cut excessive blood glucose levels at the source A uniquely collaborative study by researchers at the Salk Institute for Biological Studies uncovered a novel mechanism that turns up glucose production in the liver when blood sugar levels drop, pointing towards a new class of drugs for the treatment of metabolic disease. Their findings, published in the May 13, 2011, issue of the journal Cell, revealed a crucial role for so called histone...

2011-03-24 17:51:48

Diabetes type 2 is caused by insufficient levels of insulin to keep blood glucose under control. Excessive levels of another hormone, glucagon, can also contribute to diabetes type 2 by causing the liver to flood the body with stored glucose. Diabetes type 2 does not arise overnight, but slowly progresses for many years as a condition known as prediabetes. In prediabetes, blood sugar rises to excessive levels after a meal, but is normal or nearly normal after an overnight fast. Researchers...

2011-02-25 22:56:01

Research offers potential for new diabetes diagnostic test The death of insulin-producing beta cells in the pancreas is a core defect in diabetes. Scientists in Italy and Texas now have discovered a new way that these cells die "” by toxic imbalance of a molecule secreted by other pancreatic cells. "Our study shows that neighboring cells called alpha cells can behave like adversaries for beta cells. This was an unexpected finding," said Franco Folli, M.D., Ph.D., professor of...

2011-01-31 07:39:49

(Ivanhoe Newswire) -- About 1 million people are affected by type 1 diabetes in the United States. According to a new study, type 1 diabetes could be converted to an asymptomatic, non-insulin dependent disorder by eliminating the actions of a specific hormone. Type 1 diabetes is typically first diagnosed in children and teenagers. It is a disease where the body doesn't produce insulin -- a hormone that is needed to convert sugars, starches, and other food into energy. Glucagon is a hormone...

2011-01-27 15:26:34

Type 1 diabetes could be converted to an asymptomatic, non-insulin-dependent disorder by eliminating the actions of a specific hormone, new findings by UT Southwestern Medical Center researchers suggest. These findings in mice show that insulin becomes completely superfluous and its absence does not cause diabetes or any other abnormality when the actions of glucagon are suppressed. Glucagon, a hormone produced by the pancreas, prevents low blood sugar levels in healthy individuals. It causes...

2010-11-12 06:00:00

DANBURY, Conn., Nov. 12, 2010 /PRNewswire/ -- Scientists from Biodel Inc. (Nasdaq: BIOD) reported new findings from the company's Linjeta(TM), insulin glargine, "smart" basal insulin and stabilized glucagon development programs in poster presentations yesterday and today at the Tenth Annual Diabetes Technology Meeting in Bethesda, MD. Dr. Frank Flacke presented results of a Phase 1 single-center, double-blind, randomized crossover trial in 13 subjects with type 1 diabetes who received a...

2010-09-20 18:42:30

Biologists have found that a key protein that regulates the biological clocks of mammals also regulates glucose production in the liver and that altering the levels of this protein can improve the health of diabetic mice. Their discovery, detailed in this week's advanced online publication of the journal Nature Medicine, provides an entirely new biochemical approach for scientists to develop treatments for obesity and type 2 diabetes. It also raises the interesting possibility that some of...

2010-06-28 08:00:00

INDIANAPOLIS, June 28 /PRNewswire-FirstCall/ -- Marcadia Biotech, Inc. and Eli Lilly and Company (NYSE: LLY) today announced that the companies have signed a development and exclusive license agreement for Marcadia's short-acting glucagon program, covering glucagon analogs that may provide greater convenience and ease-of-use than the current recombinant glucagon for the treatment of severe hypoglycemia. The program includes MAR531, a glucagon analog that is in preclinical development at...

2010-06-15 16:13:42

Blocking hormone lowers sensitivity to sugar, opening door for food additives or drugs A hormone that helps to regulate blood sugar levels may also influence a person's sensitivity to sweet-tasting foods, according to a new study from researchers at the University of Maryland School of Medicine. They found that blocking the tongue's ability to respond to the hormone known as glucagon decreases the taste system's sensitivity to sweetness. That is, changing the actions of the hormone glucagon...


Latest Glucagon Reference Libraries

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2010-12-03 18:12:26

Insulin, a hormone, is used to regulate carbohydrate and fat metabolism in the body. Insulin causes cells to take up glucose from the blood and store it as glycogen in the liver and muscle. This hormone stops the body from using fat as an energy source by inhibiting the release of glucagons. Without insulin the body fails to take glucose into the bodies cells and in turns uses fat as an energy source. It also has several other anabolic effects throughout the body. Diabetes mellitus results...

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