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Latest Glucocorticoids Stories

2008-09-03 09:00:46

Akorn-Strides has announced the approval of two abbreviated new drug applications for dexamethasone sodium phosphate injection USP, 4mg (base)/mL in 1mL, 5mL, and 30mL vials, and dexamethasone sodium phosphate injection USP, 10mg (base)/mL in 10mL vials. Dexamethasone sodium phosphate injection is indicated to treat various conditions such as endocrine disorders, arthritis, blood disorders, dermatologic diseases, severe allergic reactions, eye diseases, certain cancers, gastrointestinal...

2008-08-28 15:01:07

Something goes awry in the white blood cells of caregivers of the elderly or chronically ill to increase their disease risk, U.S. and Canadian researchers say. The researchers found that among the caregivers, even though they had normal cortisol levels in their blood, the pattern of gene expression in a type of white blood cell involved in the body's immune response, was altered so that they were relatively less responsive to the anti-inflammatory actions of cortisol. Corresponding...

2008-07-22 09:01:12

SkyePharma has announced that its development and marketing partner Mundipharma has successfully completed two Phase III clinical studies for the European development program for Flutiform, both of which have shown positive results. Study FLT-3501 assessed 182 patients, suffering from mild to moderate-severe persistent and reversible asthma, who were treated in accordance with the protocol. This randomized, open label, parallel group study compared Flutiform pMDI (100mcg fluticasone &...

2008-07-18 12:01:14

Schering-Plough has announced that Schering-Plough KK, the company's country operation in Japan, has received marketing approval for Nasonex nasal spray 50mcg for the treatment of allergic rhinitis in adult patients. Schering-Plough's Nasonex is an intranasal steroid that significantly improves nasal allergy symptoms when taken once each day. Nasonex is said to be the first intranasal steroid to be approved in Japan for once-daily administration. Nasonex is currently approved in over 100...

2008-06-24 02:30:29

Glenmark Generics, a subsidiary of Glenmark Pharmaceuticals, has received ANDA approval from the FDA for Trandolapril tablets USP 1mg, 2mg and 4mg and will immediately commence marketing and distribution of these products in the US market. Glenmark's Trandolapril is an angiotensin converting enzyme inhibitor used to treat high blood pressure and is the generic equivalent of Mavik tablets marketed by Abbott Laboratories. This recent approval coupled with the three abbreviated new drug...

2008-06-10 09:01:15

Perrigo Company has filed an abbreviated new drug application for Fluocinonide cream 0.1%, a generic version of Vanos cream 0.1%. The company believes that it is the first to file an abbreviated new drug application (ANDA) with a Paragraph IV certification against Vanos. Perrigo filed its ANDA for Fluocinonide cream, 0.1% containing a Paragraph IV Certification with the FDA and notified Medicis Pharmaceutical, the listed patent holder of its filing. Vanos (fluocinonide) cream 0.1% is a...

2007-12-27 03:00:11

By Karpel, Jill P Nelson, Harold Key words: Asthma - Dry powder inhaler - Inhaled corticosteroids - Mometasone furoate - Prednisone ABSTRACT Background: Mometasone furoate (MF), a potent synthetic inhaled corticosteroid (ICS) with a high affinity for the glucocorticoid receptor, is approved for use in the treatment of asthma. Scope: Publications reviewed in this article were identified via searches of MEDLINE and EMBASE databases using the terms 'mometasone furoate AND pharmacology' and...

2007-10-23 06:00:18

By Storms, William Yawn, Barbara; Fromer, Leonard Key words: Congestion - Nasal obstruction - Nasal polyposis - Rhinitis - Rhinosinusitis - Sleep ABSTRACT Background: Patients with inflammatory disorders of the upper airways, such as allergic rhinitis, rhinosinusitis, and nasal polyposis, often have significant sleep disturbances. Poor sleep can lead to fatigue, daytime somnolence, impaired daytime functioning as reflected in lower levels of productivity at work or school, and a reduced...

2007-06-14 06:07:57

By de Groot, Pieter C M van Kamp, Inge L; Zweers, Evert J K; de Kroon, Cor D; van Wijngaarden, Willem J Abstract A 28-year-old primigravida with severe oligohydramnios and pre-eclamptic symptoms was found to have Cushing's syndrome caused by an adrenocortical tumor. After meternal therapy the amniotic volume normalised, but the fetus succumbed. As clinical features of pre-eclampsia and Cushing's syndrome may overlap, diagnosis can be delayed or even missed. Keywords: Cushing's syndrome,...

2007-06-10 06:00:11

By Doull, Iolo Price, David; Thomas, Mike; Hawkins, Neil; Et al Key words: Asthma - Cost-effectiveness - Fluticasone/salmeterol - Quality of life ABSTRACT Objective: To determine where in the treatment steps recommended by the British Thoracic Society and Scottish Intercollegiate Guidelines Network (BTS/SIGN) Asthma Guideline it is cost-effective to use salmeterol xinafoate/fluticasone propionate combination inhaler (SFC) (Seretide*) compared with other inhaled corticosteroid (ICS)...


Word of the Day
holluschickie
  • A 'bachelor seal'; a young male seal which is prevented from mating by its herd's older males (mated bulls defending their territory).
This comes from the Russian word for 'bachelors.'
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