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Latest Glucocorticoids Stories

2008-07-18 12:01:14

Schering-Plough has announced that Schering-Plough KK, the company's country operation in Japan, has received marketing approval for Nasonex nasal spray 50mcg for the treatment of allergic rhinitis in adult patients. Schering-Plough's Nasonex is an intranasal steroid that significantly improves nasal allergy symptoms when taken once each day. Nasonex is said to be the first intranasal steroid to be approved in Japan for once-daily administration. Nasonex is currently approved in over 100...

2008-06-24 02:30:29

Glenmark Generics, a subsidiary of Glenmark Pharmaceuticals, has received ANDA approval from the FDA for Trandolapril tablets USP 1mg, 2mg and 4mg and will immediately commence marketing and distribution of these products in the US market. Glenmark's Trandolapril is an angiotensin converting enzyme inhibitor used to treat high blood pressure and is the generic equivalent of Mavik tablets marketed by Abbott Laboratories. This recent approval coupled with the three abbreviated new drug...

2008-06-10 09:01:15

Perrigo Company has filed an abbreviated new drug application for Fluocinonide cream 0.1%, a generic version of Vanos cream 0.1%. The company believes that it is the first to file an abbreviated new drug application (ANDA) with a Paragraph IV certification against Vanos. Perrigo filed its ANDA for Fluocinonide cream, 0.1% containing a Paragraph IV Certification with the FDA and notified Medicis Pharmaceutical, the listed patent holder of its filing. Vanos (fluocinonide) cream 0.1% is a...

2007-12-27 03:00:11

By Karpel, Jill P Nelson, Harold Key words: Asthma - Dry powder inhaler - Inhaled corticosteroids - Mometasone furoate - Prednisone ABSTRACT Background: Mometasone furoate (MF), a potent synthetic inhaled corticosteroid (ICS) with a high affinity for the glucocorticoid receptor, is approved for use in the treatment of asthma. Scope: Publications reviewed in this article were identified via searches of MEDLINE and EMBASE databases using the terms 'mometasone furoate AND pharmacology' and...

2007-10-23 06:00:18

By Storms, William Yawn, Barbara; Fromer, Leonard Key words: Congestion - Nasal obstruction - Nasal polyposis - Rhinitis - Rhinosinusitis - Sleep ABSTRACT Background: Patients with inflammatory disorders of the upper airways, such as allergic rhinitis, rhinosinusitis, and nasal polyposis, often have significant sleep disturbances. Poor sleep can lead to fatigue, daytime somnolence, impaired daytime functioning as reflected in lower levels of productivity at work or school, and a reduced...

2007-06-14 06:07:57

By de Groot, Pieter C M van Kamp, Inge L; Zweers, Evert J K; de Kroon, Cor D; van Wijngaarden, Willem J Abstract A 28-year-old primigravida with severe oligohydramnios and pre-eclamptic symptoms was found to have Cushing's syndrome caused by an adrenocortical tumor. After meternal therapy the amniotic volume normalised, but the fetus succumbed. As clinical features of pre-eclampsia and Cushing's syndrome may overlap, diagnosis can be delayed or even missed. Keywords: Cushing's syndrome,...

2007-06-10 06:00:11

By Doull, Iolo Price, David; Thomas, Mike; Hawkins, Neil; Et al Key words: Asthma - Cost-effectiveness - Fluticasone/salmeterol - Quality of life ABSTRACT Objective: To determine where in the treatment steps recommended by the British Thoracic Society and Scottish Intercollegiate Guidelines Network (BTS/SIGN) Asthma Guideline it is cost-effective to use salmeterol xinafoate/fluticasone propionate combination inhaler (SFC) (Seretide*) compared with other inhaled corticosteroid (ICS)...

2006-02-17 14:41:07

By Clementine Wallace NEW YORK (Reuters Health) - It is simplistic to suggest that lowering cortisol levels will promote weight loss, as some television ads claim, according to researchers at the Oregon Health and Science University in Portland. In their study, published in the Journal of Clinical Investigation, the scientists show that the hormone isn't the major factor involved in weight gain and fat distribution, and might actually come into play at a secondary level. "There's no...

2005-12-09 18:30:00

NEW YORK (Reuters Health) - Good asthma management requires appropriate treatment of persistent stuffy nose or "allergic rhinitis," researchers report in the journal Chest. "We must treat rhinitis as part of asthma treatment because we can control asthma with a lower dose of inhaled steroid," Dr. Rafael Stelmach from University of Sao Paulo School of Medicine, Brazil told Reuters Health. Treating the inflammation associated with allergic rhinitis influences the control of asthma. However, few...

2005-09-02 16:04:48

The immunosuppressive drug mycophenolate mofetil, used to prevent rejection of transplanted hearts, kidneys and livers, may also be effective in controlling inflammatory eye diseases, according to a study by researchers at Johns Hopkins' Wilmer Eye Institute. "The drug seemed to be effective even in patients who had failed treatment from other immunosuppressive drugs," says lead author Jennifer E. Thorne, M.D., an assistant professor of ophthalmology. Physicians gave the drug to 84 patients,...