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Latest Glucose-6-phosphate dehydrogenase deficiency Stories

2012-11-14 13:04:56

In malaria-endemic countries, 350 million people are predicted to be deficient in an enzyme that means they can suffer severe complications from taking primaquine, a key drug for treating relapsing malaria, according to a study funded by the Wellcome Trust and published in this week's PLOS Medicine. This finding is important as primaquine is recommended in the global action plan to eliminate malaria and is the only drug to prevent malaria relapse. The benefits of implementing a treatment...

2011-03-02 20:32:17

Metabolic function for tumor suppressor points to new cancer therapeutics The gene for the protein p53 is the most frequently mutated in human cancer. It encodes a tumor suppressor, and traditionally researchers have assumed that it acts primarily as a regulator of how genes are made into proteins. Now, researchers at the University of Pennsylvania School of Medicine show that the protein has at least one other biochemical activity: controlling the metabolism of the sugar glucose, one of...

2010-01-04 13:32:05

New research in the FASEB Journal reports that the G6PD protein, which produces the essential antioxidant NAPDH, could prevent the death of pancreatic beta cells, the root cause of diabetes A new research discovery published online in the FASEB Journal (http://www.fasebj.org) may change the perception and treatment of diabetes. That's because scientists have moved closer toward correcting the root cause of the disease rather than managing its symptoms. Specifically researchers identified a...

2009-05-11 07:00:00

ACZONE(R) Gel 5% is the First New FDA-Approved Chemical Entity for Topical Acne Treatment in a Decade CARLSBAD, Calif., May 11 /PRNewswire/ -- SkinMedica, Inc. today announced that it has entered into a co-promotion agreement with Allergan for ACZONE(R) (dapsone) Gel 5%, a first-in-class topical treatment for acne vulgaris. Representing the first new molecule in a decade approved by the FDA for the topical treatment of acne in patients 12 years of age and older, ACZONE(R) Gel 5% combines...

2008-08-26 03:00:17

By Cooper, R G Magwere, T Chloroquine (CHQ) is a cheap, relatively well tolerated drug initially developed for the treatment of malaria in the 1930s. CHQ has, however, since accrued a plethora of uses in the treatment and amelioration of several other diseases and conditions because of its lysosomotropic properties. It also has characteristic physiological and systemic effects. This review gives an overview of the history and pharmacology of CHQ, and progresses to consider some of the...


Word of the Day
call-note
  • The call or cry of a bird or other animal to its mate or its young.
'Call-note' is newer than 'bird-call,' which originally referred to 'an instrument for imitating the note of birds' but now also refers to 'the song or cry of a bird.'
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