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Last updated on April 24, 2014 at 21:24 EDT

Latest Glutamate receptor Stories

2014-03-26 11:18:13

The problems people with autism have with memory formation, higher-level thinking and social interactions may be partially attributable to the activity of receptors inside brain cells, researchers at Washington University School of Medicine in St. Louis have learned. Scientists were already aware that the type of receptor in question was a potential contributor to these problems – when located on the surfaces of brain cells. Until now, though, the role of the same type of receptor...

2014-01-07 23:02:06

Two new publications by a team from Western University of Health Sciences shed further light on the mechanisms of learning and memory, and neuronal degeneration. Pomona, California (PRWEB) January 07, 2014 Two new publications by a team from Western University of Health Sciences shed further light on the mechanisms of learning and memory, and neuronal degeneration. The first paper, “A molecular brake controls the magnitude of long-term potentiation,” by Yubin Wang, Guoqi Zhu, Victor...

2013-08-08 11:02:05

Study could help yield new drugs for brain disorders Johns Hopkins biophysicists have discovered that full activation of a protein ensemble essential for communication between nerve cells in the brain and spinal cord requires a lot of organized back-and-forth motion of some of the ensemble's segments. Their research, they say, may reveal multiple sites within the protein ensemble that could be used as drug targets to normalize its activity in such neurological disorders as epilepsy,...

2013-06-25 13:15:33

Glutamate-like receptor in Arabidopsis does not detect glutamate Plants possess receptors which are similar to the glutamate receptors in the brain of humans and animals. Biochemists at the Ruhr-Universität Bochum (RUB) with colleagues from the University of Würzburg and the Agricultural University of China in Beijing have discovered that these receptors do not, however, recognize the amino acid glutamate, but many other different amino acids. The team reports in the journal "Science...

2013-05-29 09:48:10

For several years, the pharmaceutical industry has tried to develop drugs that target a specific neurotransmitter receptor in the brain, the NMDA receptor. This receptor is present on almost every neuron in the human brain and is involved in learning and memory. NMDA receptors also have been implicated in several neurological and psychiatric conditions such as Alzheimer's disease, Parkinson's disease, schizophrenia and depression. But drug companies have had little success developing...

Nitric Oxide Keeps Stroke-damaged Brain From Repairing Itself
2013-02-04 15:13:42

Sanford-Burnham Medical Research Institute In stroke and other neurological disorders, nitric oxide damages neurons and blocks the brain's ability to repair itself Nitric oxide, a gaseous molecule produced in the brain, can damage neurons. When the brain produces too much nitric oxide, it contributes to the severity and progression of stroke and neurodegenerative diseases such as Alzheimer's. Researchers at Sanford-Burnham Medical Research Institute recently discovered that nitric oxide...

2013-01-01 10:47:31

Jackson Laboratory researchers led by Associate Professor Zhong-wei Zhang, Ph.D., have provided direct evidence that a specific neurotransmitter receptor is vital to the process of pruning synapses in the brains of newborn mammals. Faulty pruning at this early developmental stage is implicated in autism-spectrum disorders and schizophrenia. The definitive evidence for N-methyl-D-aspartate receptor (NMDAR) in pruning has eluded researchers until now, but in research published in the...

2012-11-30 11:53:28

Findings from a new study in Biological Psychiatry A potential new therapeutic strategy for treating Fragile X syndrome is detailed in a new report appearing in the current issue of Biological Psychiatry, from researchers led by Dr. Lucia Ciranna at University of Catania in Italy. Fragile X syndrome (FXS), the most common heritable form of autism and intellectual disability, is one of the most exciting areas in brain research at the moment. A decade ago, Dr. Mark Bear and his...

2012-10-22 19:21:07

WOODCLIFF LAKE, N.J., Oct. 22, 2012 /PRNewswire/ -- Eisai Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved FYCOMPA (perampanel) as an adjunctive treatment for partial-onset seizures with or without secondarily generalized seizures in patients with epilepsy age 12 and older. FYCOMPA is the first FDA-approved non-competitive AMPA glutamate receptor antagonist. (Logo: http://photos.prnewswire.com/prnh/20120413/MM87168LOGO) "The FDA approval of FYCOMPA is an...

2011-10-26 13:12:34

RUB scientists decipher the role of calcium signals Bochum's neurobiologists have found that certain receptors for the neurotransmitter glutamate determine the architecture of nerve cells in the developing brain. Individual receptor variants lead to especially long and branched processes called dendrites, which the cells communicate with. The researchers also showed that the growth-promoting property of the receptors is linked to how much calcium they allow to flow into the cells....