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Latest Glutamic acid Stories

2012-02-21 14:06:49

Researchers at the University of Copenhagen have designed, produced and patented a new chemical compound for the possible treatment of brain damage caused by stroke. The compound binds 1,000 times more effectively to the target protein in the brain than the potential drug currently being tested on stroke victims. The results of biological tests have just been published in the renowned journal PNAS. More than 140,000 people die each year from stroke in the United States. Stroke causes the...

2011-11-04 20:55:19

Researchers from Virginia Commonwealth University Massey Cancer Center and the VCU Institute of Molecular Medicine have discovered a mechanism by which glioblastoma multiforme (GBM), the most common form of brain cancer, promotes the loss of function or death of neurons, a process known as neurodegeneration. The findings could lead to new therapies that suppress neurodegeneration caused by GBM and, potentially, a variety of other neurodegenerative diseases. The study, recently published in...

2011-10-26 13:12:34

RUB scientists decipher the role of calcium signals Bochum's neurobiologists have found that certain receptors for the neurotransmitter glutamate determine the architecture of nerve cells in the developing brain. Individual receptor variants lead to especially long and branched processes called dendrites, which the cells communicate with. The researchers also showed that the growth-promoting property of the receptors is linked to how much calcium they allow to flow into the cells....

2011-10-19 20:20:33

OPHN1 is found to be essential for mGluR-dependent long-term depression at synapses Scientists at Cold Spring Harbor Laboratory (CSHL) have solved part of a puzzle concerning the relationship between changes in the strength of synapses — the tiny gaps across which nerve cells in the brain communicate — and dysfunctions in neural circuits that have been linked with drug addiction, mental retardation and other cognitive disorders. A team led by CSHL Professor Linda Van Aelst...

2011-10-11 17:55:39

A tiny piece of a critical receptor that fuels the brain and without which sentient beings cannot live has been discovered by University at Buffalo scientists as a promising new drug target for Alzheimer's and other neurodegenerative diseases. The research on the NMDA (N-methyl-D-aspartate) receptor is being published online Oct. 11 in Nature Communications. "This is the first time that this site has been shown to be useful as a drug target," says Gabriela K. Popescu, PhD, associate...

2011-09-14 05:30:28

(Ivanhoe Newswire) -- Glioma, one of the most deadly and common types of brain tumor, is often associated with seizures, but the origins of these seizures and effective treatments for them have been elusive. Scientists have found that human gliomas implanted in mice release excess levels of the brain chemical glutamate, overstimulating neurons near the tumor and triggering seizures. The researchers also found that sulfasalazine, a drug on the market for treating certain inflammatory...

2011-08-17 12:16:52

Findings could be used to develop treatments to protect other nerve cell types responsible for speech and movement Neuroscientists have identified a natural protection mechanism in some of the brain's nerve cells during the onset of stroke. The findings, published today [17 August] in the Journal of Neuroscience, could be used to develop treatments to protect other nerve cell types responsible for speech and movement. Stroke "” the third largest cause of death in the UK "” causes...

2011-07-05 23:10:20

Binghamton University researcher Christof Grewer thinks he has an important brain transport protein "“ glutamate transporter "“ figured out. And he's using a novel approach to spy on them by taking aim with lasers. Grewer, a biophysical chemist, studies glutamate transport proteins, miniscule components of our brains that move glutamate among cells. Glutamate, an important molecule in cellular metabolism, is also a neurotransmitter. He explains his research on these tiny proteins...

2011-04-26 23:32:16

Structure of GluN2D subunit when docked with certain neurotransmitters helps explain the receptor's slow deactivation Structural biologists at Cold Spring Harbor Laboratory (CSHL) in collaboration with colleagues at Emory University have determined the molecular structure of a key portion, or subunit, of a receptor type commonly expressed in brain cells. The receptor is one of several NMDA (N-methyl-D-aspartate) receptor variants, and the subunit in question is that which specifically binds...

2011-04-13 15:31:53

Individuals with fragile X syndrome, the most common inherited form of intellectual disability, often develop epilepsy, but so far the underlying causes are unknown. Researchers have now discovered a potential mechanism that may contribute to the link between epilepsy and fragile X syndrome. The protein that is missing in fragile X syndrome, FMRP, controls the production of a protein that regulates electrical signals in brain cells, scientists at Emory University School of Medicine have...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.