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Latest Glycomics Stories

2012-06-11 11:53:36

Technique will help scientists understand how cells' common sugar molecules influence inflammation, cancer metastasis, and related conditions Scientists at The Scripps Research Institute have developed chemical compounds that can make key modifications to common sugar molecules ("glycans"), which are found on the surface of all cells in our body. The new study presents powerful new tools for studying these molecules' function, for example in cell signaling and immunity, and for...

2012-06-08 10:15:47

University of Alberta researchers found a chink in the molecular armor of the pathogen Acinetobacter baumannii There's new hope for development of an antibiotic that can put down a lethal bacteria or superbug linked to the deaths of hundreds of hospital patients around the world. Researchers from the University of Alberta-based Alberta Glycomics Centre found a chink in the molecular armour of the pathogen Acinetobacter baumannii. The bacteria first appeared in the 1970's and in the last...

2012-03-27 11:46:47

The traditional way of making medicines from ingredients mixed together in a factory may be joined by a new approach in which doctors administer the ingredients for a medicine separately to patients, and the ingredients combine to produce the medicine inside patients' bodies. That's one promise from an emerging new field of chemistry, according to the scientist who founded it barely a decade ago. Carolyn Bertozzi, Ph.D., spoke on the topic – bioorthogonal chemistry – here today...

2012-03-26 23:33:20

Escherichia coli — a bacteria considered the food safety bane of restaurateurs, grocers and consumers — is a friend. Cornell University biomolecular engineers have learned to use E. coli to produce sugar-modified proteins for making pharmaceuticals cheaper and faster. (Nature Chemical Biology, March 25, 2012.) Matthew DeLisa, Cornell associate professor of chemical and biomolecular engineering, and his research team, now have published a novel method for engineering human...

2011-06-16 21:35:32

Glycomics is the functional study of the entire set of sugars found in a given species. To some, the term may sound like a distant cousin of more familiar names such as genomics and proteomics. Indeed, while genomics and proteomics of several species have been extensively investigated in the last years, glycomics is still an emerging field. Now, a paper published in Science magazine by an international collaboration headed by Dr. Jose Estevez (University of Buenos Aires, Argentina) and...

2011-02-04 00:54:01

Work may have broad implications for drug development A team of scientists at The Scripps Research Institute has discovered a new way to stabilize proteins "” the workhorse biological macromolecules found in all organisms. Proteins serve as the functional basis of many types of biologic drugs used to treat everything from arthritis, anemia, and diabetes to cancer. As described in the February 4, 2011 edition of the journal Science, when the team attached a specific oligomeric array of...

2010-12-06 14:15:26

Sugar molecules coat every cell in our bodies and play critical roles in development and disease, yet the components of these "glycans" have been difficult for scientists to study, because of their complexity. Researchers at Emory University School of Medicine have adapted gene chip microarray technology to the study of glycans, with an approach they call "shotgun glycomics." The Emory team has developed a new chemical method for attaching a fluorescent dye to glycans purified from cells. The...


Word of the Day
bellycheer
  • Good cheer; viands.
  • To revel; to feast.
The word 'bellycheer' may come from 'belle cheer', "good cheer".
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