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Latest Glycomics Stories

2012-03-27 11:46:47

The traditional way of making medicines from ingredients mixed together in a factory may be joined by a new approach in which doctors administer the ingredients for a medicine separately to patients, and the ingredients combine to produce the medicine inside patients' bodies. That's one promise from an emerging new field of chemistry, according to the scientist who founded it barely a decade ago. Carolyn Bertozzi, Ph.D., spoke on the topic – bioorthogonal chemistry – here today...

2012-03-26 23:33:20

Escherichia coli — a bacteria considered the food safety bane of restaurateurs, grocers and consumers — is a friend. Cornell University biomolecular engineers have learned to use E. coli to produce sugar-modified proteins for making pharmaceuticals cheaper and faster. (Nature Chemical Biology, March 25, 2012.) Matthew DeLisa, Cornell associate professor of chemical and biomolecular engineering, and his research team, now have published a novel method for engineering human...

2011-06-16 21:35:32

Glycomics is the functional study of the entire set of sugars found in a given species. To some, the term may sound like a distant cousin of more familiar names such as genomics and proteomics. Indeed, while genomics and proteomics of several species have been extensively investigated in the last years, glycomics is still an emerging field. Now, a paper published in Science magazine by an international collaboration headed by Dr. Jose Estevez (University of Buenos Aires, Argentina) and...

2011-02-04 00:54:01

Work may have broad implications for drug development A team of scientists at The Scripps Research Institute has discovered a new way to stabilize proteins "” the workhorse biological macromolecules found in all organisms. Proteins serve as the functional basis of many types of biologic drugs used to treat everything from arthritis, anemia, and diabetes to cancer. As described in the February 4, 2011 edition of the journal Science, when the team attached a specific oligomeric array of...

2010-12-06 14:15:26

Sugar molecules coat every cell in our bodies and play critical roles in development and disease, yet the components of these "glycans" have been difficult for scientists to study, because of their complexity. Researchers at Emory University School of Medicine have adapted gene chip microarray technology to the study of glycans, with an approach they call "shotgun glycomics." The Emory team has developed a new chemical method for attaching a fluorescent dye to glycans purified from cells. The...

2010-09-11 02:10:21

The glycome, encompassing all of the complex sugars produced by an organism, is comprised of multiple families of molecules whose function in the human body is often determined by the structure, composition, and placement of the attached sugars, as explored in a comprehensive look at the field of glycomics in a group of key articles in OMICS: A Journal of Integrative Biology, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com). The relevant articles are available...

2010-08-13 16:34:56

Scientists are turning to a decades-old technique to better understand the physical effects of compression on macromolecules and how it might impact their research in proteomics, mass spectrometry, protein extraction, and tissue investigations, reports Genetic Engineering & Biotechnology News (GEN). These studies are built upon the early ultrahigh pressure discoveries of the late Nobel Prize winner in Physics, Percy Bridgman, Ph.D., who was a professor at Harvard from 1908 to 1954,...

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2010-05-31 07:32:46

Researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC), Berkeley, have successfully attached imaging probes to glycans "“ the sugar molecules that are abundant on the surfaces of living cells "“ in the embryos of zebrafish less than seven hours after fertilization. Glycans are key regulators of the processes that guide cell development, and zebrafish are a top vertebrate model organism of...


Word of the Day
cenobite
  • One of a religious order living in a convent or in community; a monk: opposed to anchoret or hermit (one who lives in solitude).
  • A social bee.
This word comes from the Latin 'coenobium,' convent, which comes from the Greek 'koinobios,' living in community.
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