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Latest Glycosylation Stories

One Of Cancer's Tricks Determined By Chemists
2012-08-23 14:31:00

Caltech chemists determine 1 way tumors meet their growing needs Behaving something like ravenous monsters, tumors need plentiful supplies of cellular building blocks such as amino acids and nucleotides in order to keep growing at a rapid pace and survive under harsh conditions. How such tumors meet these burgeoning demands has not been fully understood. Now chemists at the California Institute of Technology (Caltech) have shown for the first time that a specific sugar, known as GlcNAc...

2012-08-22 12:13:28

As a step toward designing the first effective vaccine against HIV, the virus that causes AIDS, scientists are reporting new insights into how a family of rare, highly potent antibodies bind to HIV and neutralize it – stop it from infecting human cells. The antibodies were isolated from people infected with HIV and work against a wide range of HIV strains. The researchers described the study today at the 244th National Meeting & Exposition of the American Chemical Society, the...

2012-04-03 05:31:28

(Ivanhoe Newswire) -- It is a known fact that sugar found in food is bad for teeth and the waistline, but now another sugar produced in the body's cells is implicated as a health hazard and blocking it may bring benefits that include treating cancer and improving long-term memory in older people. The sugar is not table sugar, it is a substance produced in the body's cells that qualify as sugars because of its chemical standing. Its name is "oh-glick-nack," O-linked beta-N-acetyl...

2012-03-28 09:05:27

Just as the familiar sugar in food can be bad for the teeth and waistline, another sugar has been implicated as a health menace and blocking its action may have benefits that include improving long-term memory in older people and treating cancer. Progress toward finding such a blocker for the sugar – with the appropriately malicious-sounding name "oh-glick-nack" – was the topic of a report here today at the 243rd National Meeting & Exposition of the American Chemical...

2012-03-26 23:33:20

Escherichia coli — a bacteria considered the food safety bane of restaurateurs, grocers and consumers — is a friend. Cornell University biomolecular engineers have learned to use E. coli to produce sugar-modified proteins for making pharmaceuticals cheaper and faster. (Nature Chemical Biology, March 25, 2012.) Matthew DeLisa, Cornell associate professor of chemical and biomolecular engineering, and his research team, now have published a novel method for engineering human...

2011-02-04 00:54:01

Work may have broad implications for drug development A team of scientists at The Scripps Research Institute has discovered a new way to stabilize proteins "” the workhorse biological macromolecules found in all organisms. Proteins serve as the functional basis of many types of biologic drugs used to treat everything from arthritis, anemia, and diabetes to cancer. As described in the February 4, 2011 edition of the journal Science, when the team attached a specific oligomeric array of...

2010-07-15 16:20:40

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, has discovered the gene mutation responsible for a condition in which eye and brain development is severely disrupted in affected infants. They also suggest a potential remedy that would involve a simple, daily dietary supplement. The condition is one of the congenital disorders of glycosylation or CDG, a group of syndromes in which inborn metabolic errors result in serious,...

2010-05-06 09:00:00

MILFORD, Mass. and DUBLIN, May 6 /PRNewswire/ -- Waters Corporation (NYSE : WAT) and Ireland's National Institute for Bioprocessing Research and Training (NIBRT) announced today a collaboration that will create the world's first database for glycan analysis by UltraPerformance Liquid Chromatography(®) (UPLC(®)). Expected to be available in 2011, NIBRT will develop, maintain and license the database while Waters and NIBRT will co-market it worldwide....


Word of the Day
cenobite
  • One of a religious order living in a convent or in community; a monk: opposed to anchoret or hermit (one who lives in solitude).
  • A social bee.
This word comes from the Latin 'coenobium,' convent, which comes from the Greek 'koinobios,' living in community.
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