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Latest Granulocyte macrophage colony-stimulating factor Stories

2014-01-03 11:31:48

Mycobacterium tuberculosis is a major cause of death worldwide, and a formidable foe. Most healthy people can defend themselves against tuberculosis, but they need all parts of their immune system to work together. A study published on January 2nd in PLOS Pathogens reveals how a special class of immune cells called "invariant natural killer T cells" make their contribution to this concerted effort. "We were interested in identifying the mechanisms that different types of T cells use to...

2013-12-16 18:14:37

Rates of programmed cell death higher in mice treated with experimental drug than in untreated animals with same cancer An experimental drug that targets macrophages, a type of immune cells, in the microenvironment surrounding the lethal brain tumor glioblastoma multiforme decreased the cancer's growth and extended survival of laboratory mice with the cancer, scientists will report on Tuesday Dec. 17, at the American Society for Cell Biology (ASCB) annual meeting in New Orleans. The...

2013-11-18 20:57:58

Joseph Poole, M.D., Ph.D., of the Emory University School of Medicine, Atlanta, and colleagues studied whether therapy with granulocyte-macrophage colony stimulating factor (GM-CSF), an agent that functions as a white blood cell growth factor, would improve walking performance in patients with symptomatic peripheral artery disease (a form of vascular disease in which there is partial or total blockage of an artery, usually one leading to a leg or arm). "Peripheral artery disease (PAD)...

2013-08-07 10:19:58

Novel treatment boosted selective immune attack on leukemia cells in post-transplant patients Patients with advanced chronic lymphocytic leukemia (CLL) often receive donor transplants that effectively "reboot" their own immune defenses, which then attack and potentially cure the hard-to-treat disease. However, there is a high rate of relapse in these patients, and the transplanted immune cells may also harm normal tissues, causing graft-versus-host disease (GVHD). Now, scientists at...

2012-08-21 23:21:50

The research relates to a family of molecules firstly discovered in Melbourne that applied to blood cell development. One of these, granulocyte macrophage colony-stimulating factor or GM-CSF, acts as a messenger between cells acting at a site of inflammation. Professor John Hamilton has posed the question: could blocking GM-CSF action lead to a new treatment for inflammatory diseases? In experimental models of rheumatoid arthritis, Professor Hamilton and Dr Andrew Cook had previously shown...

2012-06-22 12:03:36

The same growth factor was previously shown to reverse memory decline in Alzheimer´s mice Growth factors shown to cure Alzheimer´s disease in a mouse model and administered to cancer patients as part of their treatment regimen were linked to significant improvements in the patients´ cognitive function following stem cell transplantation, a preliminary clinical study reports. The findings by researchers at the USF Health Byrd Alzheimer´s Institute and Moffitt Cancer...

2011-08-16 06:30:00

ATLANTA, Aug. 16, 2011 /PRNewswire/ -- GeoVax Labs, Inc. (OTCQB/OTCBB: GOVX), an Atlanta-based, biopharmaceutical firm developing vaccines to prevent and fight Human Immunodeficiency Virus (HIV) infections, today announced receipt of a $3.6 million annual notice of award for the Integrated Preclinical/Clinical AIDS Vaccine Development (IPCAVD) Grant supporting GeoVax's HIV/AIDS vaccine program. This grant was originally awarded in 2007 to GeoVax by the National Institutes of...

2011-06-08 06:00:00

ATLANTA, June 8, 2011 /PRNewswire/ -- GeoVax Labs, Inc. (OTCQB/OTCBB: GOVX) announced today the publication of the results of preclinical testing of a simian prototype of its 2nd generation HIV/AIDS vaccine. The article, titled "Prevention of Infection by a Granulocyte-Macrophage Colony-Stimulating Factor Co-Expressing DNA/Modified Vaccinia Ankara Simian Immunodeficiency Virus Vaccine," will appear in the July 1 issue of The Journal of Infectious Diseases. A PDF of the article can be...


Word of the Day
vermicular
  • Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
  • Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
  • Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
  • A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.
This word ultimately comes from the Latin 'vermis,' worm.
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