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Last updated on April 18, 2014 at 17:24 EDT

Latest Granulocytes Stories

Portable Counter For White Blood Cells Being Developed
2013-03-26 10:25:03

California Institute of Technology White blood cells, or leukocytes, are the immune system's warriors. So when an infection or disease attacks the body, the system typically responds by sending more white blood cells into the fray. This means that checking the number of these cells is a relatively easy way to detect and monitor such conditions. Currently, most white blood cell counts are performed with large-scale equipment in central clinical laboratories. If a physician collects blood...

2013-03-19 14:20:06

Potential approach to treating atherosclerosis and other chronic inflammatory diseases A multicenter team of researchers, including scientists at Columbia University Medical Center (CUMC), Brigham and Women's Hospital (BWH), Mount Sinai School of Medicine, and Massachusetts Institute of Technology, has developed biodegradable nanoparticles that are capable of delivering inflammation-resolving drugs to sites of tissue injury. The nanoparticles, which were successfully tested in mice, have...

2012-07-02 21:34:23

Novel mechanism plays major role in inflammation Like detectives seeking footprints and other clues on a television "whodunit," science can also benefit from analyzing the tracks of important players in the body's molecular landscape. Klaus Ley, M.D., a scientist at the La Jolla Institute for Allergy & Immunology, has done just that and illuminated a key step in the journey of inflammation-producing immune cells. The finding provides powerful, previously unknown information about...

2012-02-28 21:50:43

University of Texas Medical Branch at Galveston researchers have discovered previously unsuspected aspects of the guidance system used by the body's first line of defense against infection. The new work focuses on the regulation of immune response by two forms of the signaling molecule IL-8, as well as IL-8's interaction with cell-surface molecules called glycosaminoglycans (or GAGs for short). Infected or injured tissues release IL-8 to attract bacteria- and virus-killing white blood...

2011-12-02 01:52:22

Discovery provides new insights on role of histamine releasing factor in asthma and allergies La Jolla Institute for Allergy & Immunology scientists have identified the histamine releasing factor (HRF) molecule as a promising target for developing new treatments for a number of allergic reactions including asthma. The research team, led by Toshiaki Kawakami, M.D., Ph.D., is also the first to clarify the role of the HRF molecule in promoting asthma and some allergies, including...

2011-06-27 14:17:26

A study from scientists at Queen Mary, University of London, sheds new light on why people who experience serious trauma or go through major surgery, can suffer organ damage in parts of the body which are seemingly unconnected to the injury. The study, published today in Nature Immunology*, examines the way certain white blood cells, called neutrophils move out of blood vessels to defend damaged organs against injury or infection. This is normally a one-way journey but researchers were...

2011-06-05 00:02:41

SRxA Strategic Pharmaceutical Advisors, LLC, a leading healthcare consulting, marketing and education firm, is pleased to announce that it has entered into an agreement with the Executive Directors and organizers of the International Eosinophil Society, Inc. (IES) to become the exclusive provider of rapid dissemination post-symposium e-Newsletter. Washington, DC (PRWEB) June 04, 2011 SRxA Strategic Pharmaceutical Advisors, LLC, a leading healthcare consulting, marketing and education firm,...

2011-02-25 19:18:52

Heparin plays a key role in allergic and inflammatory reactions driven by mast cells, scientists from Karolinska Institutet in Sweden shows in an international collaboration involving colleagues from Germany and Switzerland. The study is published in the recent issue of Immunity, and sheds some new light on the biological function of heparin. Heparin has a long history at Karolinska Institutet, since here the substance was originally purified and its chemical structure was characterized back...

2010-10-28 21:46:53

White blood cells called neutrophils are part of the body's first line of defense against bacterial infection. Neutrophils are recruited from the bloodstream to infected tissues where they release powerful chemicals that kill bacteria and amplify the immune response. These cells function as first responders at the scene of infection and often have a short life span. As a result, new neutrophils are produced continuously from stem cells in the bone marrow. Previous research has suggested that...

2010-10-25 16:17:36

A new study reveals that two enzymes help immune cells deploy pathogen-killing traps by unraveling and using the chromatin (DNA and its associated proteins) contained in the cells' nuclei to form defensive webs. The study appears online on October 25 in The Journal of Cell Biology (www.jcb.org). Neutrophils, the most common type of white blood cells, are difficult to study because they live for only about six hours. So Arturo Zychlinsky and colleagues, from the Max Planck Institute for...