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Latest Granuloma Stories

2014-09-19 08:25:37

--Use of Crowdsourced Clinical Trial Protocols and Telemonitoring for Remote Patient Data Collection Is Potential Game-Changer for Orphan Diseases NEW YORK, Sept. 19, 2014 /PRNewswire/ -- Transparency Life Sciences, LLC (TLS), the world's first clinical-stage drug development company based on open innovation, today announced that it is applying its expertise in crowdsourcing and digital telemonitoring technology to conduct a clinical trial of Auven Therapeutics' Kiacta(TM)( )in...

2014-04-28 10:15:29

Inflammation has long been considered an integral part of the biological process that leads to deadly scarring in idiopathic pulmonary fibrosis. New research at National Jewish Health, however, suggests that a little inflammation may also be crucial to the healing and repair processes in the lungs.  Elizabeth Redente, PhD, assistant professor of cell biology at National Jewish Health, and her colleagues report in the April 2014 issue of the American Journal of Respiratory Cell and Molecular...

2013-06-19 14:06:07

Among patients with suspected stage I/II pulmonary sarcoidosis who were undergoing confirmation of the condition via tissue sampling, the use of the procedure known as endosonographic nodal aspiration compared with bronchoscopic biopsy, the current diagnostic standard, resulted in greater diagnostic yield, according to a study in the June 19 issue of JAMA. Sarcoidosis, a disease that causes granulomas (usually small masses) due to chronic inflammation in body tissues, has an estimated...

2012-02-22 21:34:08

Sometimes our immune defence attacks our own cells. When this happens in the brain we see neurodegenerative diseases such as dementia, Alzheimer´s and Parkinson´s disease. But if the the immune defence is inhibited, the results could be disastrous. Researchers at the University of Copenhagen have now discovered one of the molecular combat mechanisms in the brain that gets out of control in these diseases. In time this may enable targeted therapies to slow down the disease without...

2012-02-10 10:27:26

A neuropeptide called Substance P is the cause of seizures in patients with brains infected by the pork tapeworm (Taenia solium), said Baylor College of Medicine researchers in a report that appears online in the open access journal PLoS Pathogens. "Neurocysticercosis or the tapeworm parasitic infection in the brain, is the major cause of acquired seizures," said Dr. Prema Robinson, assistant professor of medicine — infectious diseases, and corresponding author of the report. "It is...

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2009-12-11 09:17:44

Finding how to block the pathway may lead to new therapies for TB and other disorders Scientists have discovered a signaling pathway that tuberculosis bacteria use to coerce disease-fighting cells to switch allegiance and work on their behalf. Epithelial cells line the airways and other surfaces to protect and defend the body. Tuberculosis bacteria co-opt these epithelial cells into helping create tubercles: the small, rounded masses characteristic of TB. The tubercles enable the bacteria to...

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2009-09-23 07:58:39

Researchers at the National Institute of Standards and Technology (NIST), in collaboration with private industry and other government agencies, have produced a new reference material for beryllium. Beryllium, an exotic rare-earth metal used as a hardener in high-performance alloys and ceramics, can cause berylliosis"”a chronic, incurable and sometimes fatal illness. The new reference material is expected to dramatically improve methods used to monitor workers' exposure and aid in...

2009-06-04 15:35:09

A high school teacher in Sammamish, Wash., says one of her students successfully diagnosed herself with a granuloma. Eastside Catholic High School teacher Mary Margaret Welch said her student, Jessica Terry, uncovered the secret to her failing health while researching intestinal diseases with classmates, Seattle's KOMO-TV reported Wednesday. All of a sudden she says, 'I think I found something.' I say, 'what?' 'Miss Welch, Miss Welch, come over here. I think it's a granuloma,' Welch told KOMO...

2009-05-22 08:14:55

Current research suggests that Mycobacterium tuberculosis can evade the immune response. The related report by Rahman et al, "Compartmentalization of immune responses in human tuberculosis: few CD8+ effector T cells but elevated levels of FoxP3+ regulatory T cells in the granulomatous lesions," appears in the June 2009 issue of The American Journal of Pathology. More than two million people worldwide die from tuberculosis infection every year. Due in part to inappropriate antibiotic usage,...

2008-09-18 12:00:11

By Sarah Howden THERE'S no escaping the fact that summer has been a washout. Forget the winter blues, with sunshine at an all-time low this year some experts claim it's harming our health. Many of us are said to be suffering from a deficiency of vitamin D, which is produced naturally when the body is exposed to natural sunlight. In fact, with exposure to less than an average of 20 minutes sunlight a day, the average Scot has vitamin D levels four times lower than our southern...


Word of the Day
humgruffin
  • A terrible or repulsive person.
Regarding the etymology of 'humgruffin,' the OED says (rather unhelpfully) that it's a 'made-up word.' We might guess that 'hum' comes from 'humbug' or possibly 'hum' meaning 'a disagreeable smell,' while 'gruffin' could be a combination of 'gruff' and 'griffin.'