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Researchers at Brown University and Women & Infants Hospital have invented the first artificial human ovary, an advance that provides a potentially powerful new means for conducting fertility research and could also yield infertility treatments for cancer patients.
Researchers have discovered that some women carry a genetic variation that makes them sub-fertile and less likely to respond to ovarian stimulating hormones during fertility treatment.
Researchers from the National Institutes of Health and other institutions have identified in mice two proteins essential for ovulation to take place.
Two enzymes called extracellular signal-regulated kinases (ERK1 and ERK2) are critical factors in a pathway that induces ovulation, maturation of the mammalian egg (oocyte) and other activities key to ovarian function and female fertility, said a group of researchers at Baylor College of Medicine (BCM) in a report that appears today in the journal Science.