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Latest Gross pathology Stories

2010-05-13 08:00:00

ALISO VIEJO, Calif., May 13 /PRNewswire/ -- Sequent Medical, Inc. announced today that it has closed a $15.6 million Series B venture capital financing. The financing was led by Domain Associates, joined by existing investors Versant Ventures and US Venture Partners. Nimesh Shah of Domain will join Sequent's Board of Directors. "We are privileged to have such a high caliber group of investors, and would like to welcome both Domain Associates as an investor in Sequent and Nimesh Shah as...

2010-04-27 14:28:47

A new theory that muscle and bone diseases affect each other could have an impact on science and the cost of getting sick Traditionally, doctors and clinicians thought diseases that affect muscles or bones affected those areas specifically. For example, bone diseases only affect bones, or muscle diseases only concerned muscles. But recent evidence supports the notion that bones and muscles are more interconnected than previously thought. It seems that bones and muscles can release signals...

2010-04-05 07:01:29

In the largest genome-wide study of brain aneurysms ever conducted, an international team led by researchers at the Yale School of Medicine has identified three new genetic variants that increase a person's risk for developing this deadly disease. The massive study of intracranial aneurysms involved more than 20,000 subjects and was published in the April 4 online edition of the journal Nature Genetics. The new study, the second by Yale researchers published within the last 15 months, brings...

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2010-03-22 08:47:58

A new study in the Journal of Cell Biology (JCB) identifies a cytokine signaling pathway that induces the breakdown of disused skeletal muscle. Blocking this pathway could prevent immobilized patients from losing their muscle tissue. The article appears in the March 22 issue of the JCB. Skeletal muscle wastes away when its activity is reduced by, for example, a spinal cord injury. Although the mechanism by which muscle fibers break down is understood fairly well, how the process is triggered...

2010-02-27 07:38:36

For people who carry common gene variants, cigarette smoking greatly increases the risk that a blood vessel in the brain will weaken and balloon out "“ called an aneurysm "“ which could be life-threatening if it ruptures, according to research presented at the American Stroke Association's International Stroke Conference 2010. Researchers reported on two new studies from the Familial Intracranial Aneurysm (FIA) project, a multinational collaboration funded by the National...

2010-02-11 11:55:12

One of first human implants of device for aortic injury in U.S. performed as part of clinical trial Scott & White Memorial Hospital vascular surgeons Clifford Buckley, M.D., and Ruth Bush, M.D., performed one of the nation's first implants of a Next Generation Conformable GORE TAG Thoracic Endoprosthesis device for the treatment of a traumatic aortic transection as part of a national clinical trial. The goal of the trial is to gain insight into using thoracic endografts for patients with...

2010-01-27 16:49:35

New research findings from a team at the Providence Heart + Lung Institute at St. Paul's Hospital and the University of British Columbia (UBC) may lead to new treatment options for abdominal aortic aneurysms (AAA) "“ a potentially fatal disease that currently has no pharmacological treatments. An aortic aneurysm is a bulging of the aorta, the largest blood vessel in the body. If the aneurysm ruptures, it causes rapid blood loss and a high risk of death. About 75 per cent of all aortic...

2010-01-04 15:22:50

New research in the FASEB Journal shows free radicals damage mitochondria in our muscle cells, resulting in age-related muscle loss If you're an aging baby boomer hoping for a buffer physique, there's hope. A team of American scientists from Texas and Michigan have made a significant discovery about the cause of age-related muscle atrophy that could lead to new drugs to halt this natural process. This research, available online the FASEB Journal (http://www.fasebj.org), shows that free...

2009-12-02 07:07:00

WALTHAM, Mass., Dec. 2 /PRNewswire/ -- According to Millennium Research Group (MRG), the global authority on medical technology market intelligence, intracranial endovascular procedures to treat aneurysms will grow at over 5% through 2014 in the US. MRG's new US Markets for Transcatheter Embolization and Occlusion Devices 2010 report finds that technological advancements in embolization coils as well as imaging and coiling-assist technology will continue to drive growth in aneurysm...

2009-12-01 14:29:14

In order to maintain muscle strength with age, cells must rid themselves of the garbage that accumulates in them over time, just as it does in any household, according to a new study in the December issue of Cell Metabolism, a Cell Press journal. In the case of cells, that waste material includes spent organelles, toxic clumps of proteins, and pathogens. The researchers made their discovery by studying mice that were deficient for a gene required for the tightly controlled process of...


Word of the Day
humgruffin
  • A terrible or repulsive person.
Regarding the etymology of 'humgruffin,' the OED says (rather unhelpfully) that it's a 'made-up word.' We might guess that 'hum' comes from 'humbug' or possibly 'hum' meaning 'a disagreeable smell,' while 'gruffin' could be a combination of 'gruff' and 'griffin.'