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Latest Growth factor Stories

2011-11-28 20:29:27

Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified a cellular protein that plays a central role in the formation of new blood vessels. The molecule is the protein Shc (pronounced SHIK), and new blood vessel formation, or angiogenesis, is seriously impaired without it. The study, which appeared online November 16, 2011 in the journal Blood, was led by associate professor of cell and molecular physiology at UNC, Ellie Tzima, PhD, who is also a...

Image 1 - Diet Key To Becoming A Queen Bee
2011-11-10 13:30:47

A honey bee becomes a royal queen or a common worker as a result of the food she receives as a larva. While it has been well established that royal jelly is the diet that makes bees queens, the molecular path from food to queen is still in dispute. However, scientists at Arizona State University, led by Adam Dolezal and Gro Amdam, have helped reconcile some of the conflicts about bee development and the role of insulin pathways and partner proteins. Their article "IIS and TOR...

2011-10-12 23:15:46

By manipulating a well-known molecular pathway, JDRF-funded scientists breathe new life into aging beta cells As a person ages, the ability of their beta cells to divide and make new beta cells declines. By the time children reach the age of 10 to 12 years, the ability of their insulin-producing cells to replicate greatly diminishes. If these cells, called beta cells, are destroyed–as they are in type 1 diabetes–treatment with the hormone insulin becomes essential to regulate...

2011-09-20 06:00:00

MADISON, Wis., Sept. 20, 2011 /PRNewswire/ -- Cellular Dynamics International (CDI) today announced the commercial launch of human iCell® Endothelial Cells for use in vascular-targeted drug discovery, tissue regeneration and other life science research. Endothelial cells make up the lining of blood vessels and thus are an important factor of vascular research across a multitude of disease states. Endothelial dysfunction is a common promoter of cardiovascular disease,...

2011-08-29 13:04:48

Ever since scientists first began growing human cells in lab dishes in 1952, they have focused on improving the chemical soup that feeds the cells and helps regulate their growth. But surfaces also matter, says Laura Kiessling, a professor of chemistry at the University of Wisconsin-Madison, who observes that living cells are normally in contact with each other and with a structure called the extracellular matrix, not just with the dissolved chemicals in their surroundings. "Soluble...

2011-08-15 22:07:30

In a new study published in the August 16th issue of Developmental Cell, researchers at NYU Langone Medical Center identified a molecular mechanism that guarantees that new blood vessels form in the right place and with the proper abundance. "We have known for a long time that blood vessels branch to give rise to new ones and that in some places of our bodies this branching occurs with a reproducible pattern. However, the mechanisms that ensure that new vessels sprout at specific locations...

2011-08-01 19:42:58

Nanostructure promotes growth of new blood vessels, mimics natural protein Tissue deprived of oxygen (ischemia) is a serious health condition that can lead to damaged heart tissue following a heart attack and, in the case of peripheral arterial disease in limbs, amputation, particularly in diabetic patients. Northwestern University researchers have developed a novel nanostructure that promotes the growth of new blood vessels and shows promise as a therapy for conditions where increased blood...

2011-07-02 02:29:20

Natural plant compound blocks vessel growth by interfering with cellular adhesion Massachusetts General Hospital (MGH) researchers have discovered the first of an entirely new class of antiangiogenesis drugs "“ agents that interfere with the development of blood vessels. In a report in Proceedings of the National Academy of Sciences/Early Edition, the investigators describe how a compound derived from a South American tree was able, through a novel mechanism, to interfere with blood...

2011-05-31 12:17:16

Scientists identify in the journal Nature a new molecular pathway used to suppress blood vessel branching in the developing retina "“ a finding with potential therapeutic value for fighting diseases of the retina and a variety of cancers. Researchers report that myeloid cells, blood cells involved in the immune system, use this molecular pathway to guide blood vessel patterning in the retina. Furthermore, in the same study researchers were able to reverse this pathway to accelerate the...

2011-04-28 00:00:27

Muscular-skeleton, joint injuries and arthritis affect over 100 million Americans, or one in every three people. A majority of these people develop chronic problems and disability. Miami Beach, FL (PRWEB) April 27, 2011 The Center for Regenerative Medicine in Miami Beach, Florida, concentrates on helping arthritic and injured people to get back to a functional level of life and their activities using non-surgical techniques and orthopedic medicine. The center's expertise is in treatment of...